Dose-Dependent Pattern of Cochlear Synaptic Degeneration in C57BL/6J Mice Induced by Repeated Noise Exposure

<div>No significant permanent effects on (a–c) ABR wave I amplitudes, (d) ribbon synapse counts, and (e) MOC efferent synaptic measurement post low-intensity (88, 91, and 94 dB SPL) repeated noise exposure. (f) Representative IF images of morphometric analysis at frequency of 22.6 kHz (the scale bar indicates 10 <i>μ</i>m). Two-way ANOVA with Bonferroni post hoc tests were used to compare the difference between groups. The error bar represents the SEM for 8-12 mice in each group. 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Neural Plasticity

fig4

Figure 4

Figure 4: Dose-Dependent Pattern of Cochlear Synaptic Degeneration in C57BL/6J Mice Induced by Repeated Noise Exposure 