Decreased Nucleus Accumbens Connectivity at Rest in Medication-Free Patients with Obsessive-Compulsive Disorder

Table 1

Demographic and clinical characteristics of participants.

	OCD patients ()	HCs ()
Age (years)			0.05	0.71
Sex (male/female)	27/13	25/13	0.03	0.87
Education (years)			−0.50	0.83
Illness duration (months)
Y-BOCS total score			25.27	<0.01
Y-BOCS obsessive thinking			17.98	<0.01
Y-BOCS compulsive behavior	12.05 ± 4.62		14.92	<0.01
HAMD			9.04	<0.01
HAMA			9.00	<0.01
FD			1.25	0.13
Time points scrubbed out			0.25	0.95

OCD: obsessive-compulsive disorder; Y-BOCS: Yale-Brown Obsessive-Compulsive Scale; HAMD: 17-item Hamilton Depression Rating Scale; HAMA: Hamilton Anxiety Rating Scale; FD: framewise displacement. Variables of age, education, Y-BOCS total score, subscales score, HAMD score, HAMA score, and FD were tested by two-sample -test; the results were indicated by values. Categorical data such as gender was tested using a chi-squared test; the result was indicated by .