Neural Plasticity

Translational Research in Bipolar Disorders


Publishing date
20 Feb 2015
Status
Published
Submission deadline
03 Oct 2014

Lead Editor

1The University of Texas Medical School at Houston, Houston, USA

2National Institute of Health, Bethesda, USA

3McMaster University, Hamilton, Canada

4University of Toronto, Toronto, Canada


Translational Research in Bipolar Disorders

Description

Bipolar disorder is a severe mood disorder with high morbidity and mortality. Despite adequate treatment, patients continue to have recurrent mood episodes, residual symptoms, and functional impairment. Although the etiology of bipolar disorder remains uncertain, multiple studies examining neuroimaging, peripheral markers, and genetics have provided important insights into the pathophysiologic processes underlying bipolar disorder. The pathophysiology of bipolar disorder includes several systemic alterations, such as inflammatory markers, oxidative stress, and DNA damage. Most of these parameters may be related to dysfunctions in cellular resilience mechanisms reported in patients, such as endoplasmic reticulum stress and mitochondrial damage. As consequence, these impairments can ultimately lead to cell death.

We invite investigators to contribute original research as well as review articles that will stimulate the continuing efforts to understand the molecular pathophysiology underlying bipolar disorder, the development of innovative strategies to treat this condition, and the evaluation of outcomes.

Potential topics include, but are not limited to:

  • Cellular in vitro studies
  • Neural plasticity
  • Animal models
  • Genetics
  • Biomarkers
  • Neuroimaging
  • Diagnostics
  • Suicide
  • Innovative treatments
  • ECT, TMS, and other therapeutic interventions
  • Clinical staging
  • Neuroprogression
  • Psychoeducation

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 576978
  • - Editorial

Translational Research in Bipolar Disorders

Rodrigo Machado-Vieira | Benicio N. Frey | ... | João Quevedo
  • Special Issue
  • - Volume 2015
  • - Article ID 692541
  • - Research Article

Preclinical Evidences for an Antimanic Effect of Carvedilol

Greicy Coelho de Souza | Julia Ariana de S. Gomes | ... | Danielle Macêdo
  • Special Issue
  • - Volume 2015
  • - Article ID 408136
  • - Review Article

The Potential Role of the NLRP3 Inflammasome as a Link between Mitochondrial Complex I Dysfunction and Inflammation in Bipolar Disorder

Helena Kyunghee Kim | Wenjun Chen | Ana Cristina Andreazza
  • Special Issue
  • - Volume 2015
  • - Article ID 165180
  • - Research Article

Normal Metabolic Levels in Prefrontal Cortex in Euthymic Bipolar I Patients with and without Suicide Attempts

Marlos Vasconcelos Rocha | Fabiana Nery-Fernandes | ... | Ângela Miranda-Scippa
  • Special Issue
  • - Volume 2015
  • - Article ID 434127
  • - Review Article

The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts

Rafaela Torres Portugal Leite | Sarah de Oliveira Nogueira | ... | Fábio Gomes de Matos e Souza
  • Special Issue
  • - Volume 2015
  • - Article ID 521398
  • - Review Article

Magnetic Seizure Therapy for Unipolar and Bipolar Depression: A Systematic Review

Eric Cretaz | André R. Brunoni | Beny Lafer
  • Special Issue
  • - Volume 2015
  • - Article ID 939780
  • - Research Article

Cytomegalovirus Antibody Elevation in Bipolar Disorder: Relation to Elevated Mood States

A. R. Prossin | R. H. Yolken | ... | M. G. McInnis
  • Special Issue
  • - Volume 2015
  • - Article ID 324825
  • - Research Article

Correlation between Peripheral Levels of Brain-Derived Neurotrophic Factor and Hippocampal Volume in Children and Adolescents with Bipolar Disorder

Tatiana Lauxen Peruzzolo | Mauricio Anes | ... | Cristian Patrick Zeni
  • Special Issue
  • - Volume 2015
  • - Article ID 708306
  • - Review Article

Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder?

Jay P. Patel | Benicio N. Frey
Neural Plasticity
 Journal metrics
Acceptance rate53%
Submission to final decision58 days
Acceptance to publication37 days
CiteScore5.200
Journal Citation Indicator0.620
Impact Factor3.599
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