Neural Plasticity

Maladaptive Plasticity and Neuropathic Pain


Publishing date
09 Oct 2015
Status
Published
Submission deadline
22 May 2015

Lead Editor

1Zhejiang University, Zhejiang, China

2Peking University, Beijing, China

3University of Texas Medical Branch, Texas, USA

4Johns Hopkins University, Baltimore, USA

5University of Maryland Dental School, Baltimore, USA

6Imperial College London, London, UK


Maladaptive Plasticity and Neuropathic Pain

Description

The neuropathic pain is caused by the injury or damage on the sensory nervous system; its pathological phenomena include allodynia, hyperalgesia, and spontaneous pain. About 4–8% of people in our society are suffering from this disease. Emerging evidences from both human patients and animal models showed that maladaptive plastic changes happened along the sensory pathways, from the peripheral to central nervous system, which may be involved in the generation, development, and maintenance of neuropathic pain. Therefore knowing the mechanisms mediating the maladaptive plasticity will be helpful for the neuropathic pain treatments in the future.

We invite investigators to contribute original research as well as review articles that will stimulate the continuing efforts to understand the molecular mechanism underlying maladaptive plasticity along sensory pathways and the development of innovative strategies to treat neuropathic pain.

Potential topics include, but are not limited to:

  • The molecular basis of neuronal plasticity along the sensory pathways
  • The long-term changes of information coding under neuropathic pain conditions
  • Maladaptive plasticity as a link between neuropathic pain (neuroimaging studies)
  • The genetic basis for the individual neuropathic pain development
  • The clinical treatments for neuropathic pain
  • The neuropathic pain and relative emotional disorders
  • Glial basis for the neuropathic pain
  • Epigenetic modification and neuropathic pain

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 4842159
  • - Editorial

Maladaptive Plasticity and Neuropathic Pain

Xiang-Yao Li | You Wan | ... | Daqing Ma
  • Special Issue
  • - Volume 2016
  • - Article ID 5954890
  • - Review Article

Emerging Role of Spinal Cord TRPV1 in Pain Exacerbation

Seung-In Choi | Ji Yeon Lim | ... | Sun Wook Hwang
  • Special Issue
  • - Volume 2016
  • - Article ID 5238730
  • - Research Article

Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model

Agnieszka M. Jurga | Ewelina Rojewska | ... | Joanna Mika
  • Special Issue
  • - Volume 2016
  • - Article ID 2130901
  • - Research Article

Bilateral Neuropathy of Primary Sensory Neurons by the Chronic Compression of Multiple Unilateral DRGs

Ya-Bin Xie | Huan Zhao | ... | Hui Xu
  • Special Issue
  • - Volume 2016
  • - Article ID 4131395
  • - Research Article

The Gate Theory of Pain Revisited: Modeling Different Pain Conditions with a Parsimonious Neurocomputational Model

Francisco Javier Ropero Peláez | Shirley Taniguchi
  • Special Issue
  • - Volume 2016
  • - Article ID 1682972
  • - Research Article

TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

Tunyu Jian | Niuniu Yang | ... | Zongxiang Tang
  • Special Issue
  • - Volume 2015
  • - Article ID 394820
  • - Research Article

Activation of the Mammalian Target of Rapamycin in the Rostral Ventromedial Medulla Contributes to the Maintenance of Nerve Injury-Induced Neuropathic Pain in Rat

Jian Wang | Da-Yun Feng | ... | Yun-Qing Li
  • Special Issue
  • - Volume 2015
  • - Article ID 453170
  • - Research Article

Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice

Zhen-Xing Zuo | Yong-Jie Wang | ... | Xiang-Yao Li
  • Special Issue
  • - Volume 2015
  • - Article ID 249756
  • - Research Article

Upregulation of EMMPRIN (OX47) in Rat Dorsal Root Ganglion Contributes to the Development of Mechanical Allodynia after Nerve Injury

Qun Wang | Yanyuan Sun | ... | Yan Lu
  • Special Issue
  • - Volume 2015
  • - Article ID 752782
  • - Research Article

A Novel Nitronyl Nitroxide with Salicylic Acid Framework Attenuates Pain Hypersensitivity and Ectopic Neuronal Discharges in Radicular Low Back Pain

Wen-Juan Han | Lei Chen | ... | Ceng Luo
Neural Plasticity
 Journal metrics
Acceptance rate53%
Submission to final decision58 days
Acceptance to publication37 days
CiteScore6.900
Impact Factor3.093
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