Neural Plasticity

CNS Plasticity in Injury and Disease


Status
Published

1Emory University, Atlanta, USA

2University of Kentucky, Lexington, USA

3University of California, San Francisco, USA


CNS Plasticity in Injury and Disease

Description

The central nervous system (CNS) undergoes many changes in trauma and disease, not all deleterious. The prior dogmatic belief that regeneration does not occur in the adult CNS has been disproven. Both neurons and oligodendrocytes undergo organized apoptotic cell death after CNS injury, and both cell types have the capacity to undergo some measure of regeneration after injury.

In fact, the microenvironment of the injured CNS may be especially supportive of plasticity due to inflammation and release of trophic factors. Reparative and compensatory events may occur at several levels including synaptic changes, neuronal and glial regeneration, and development of compensatory systems.

We invite investigators to contribute original research as well as review articles that examine plasticity in the CNS after injury and in disease.

Potential topics include, but are not limited to:

  • Neurogenesis after CNS trauma
  • Regeneration in CNS disease
  • Synaptic changes in trauma and disease
  • Neuronal and glial death and regeneration after injury
  • Stem cell biology in the injured nervous system
  • Therapies for enhancing CNS plasticity after injury
  • Effects of neuroinflammation on CNS plasticity
  • Clinical evidence for plasticity after CNS injury

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 1923950
  • - Editorial

CNS Plasticity in Injury and Disease

Brandon A. Miller | John C. Gensel | Michael S. Beattie
  • Special Issue
  • - Volume 2016
  • - Article ID 2769735
  • - Review Article

Neuroplasticity and Repair in Rodent Neurotoxic Models of Spinal Motoneuron Disease

Rosario Gulino
  • Special Issue
  • - Volume 2015
  • - Article ID 608581
  • - Review Article

Physical Exercise as a Diagnostic, Rehabilitation, and Preventive Tool: Influence on Neuroplasticity and Motor Recovery after Stroke

Caroline Pin-Barre | Jérôme Laurin
  • Special Issue
  • - Volume 2015
  • - Article ID 138979
  • - Review Article

Synaptic Plasticity and Neurological Disorders in Neurotropic Viral Infections

Venkata Subba Rao Atluri | Melissa Hidalgo | ... | Madhavan Nair
  • Special Issue
  • - Volume 2015
  • - Article ID 798481
  • - Research Article

Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

Maya Weinstein | Vicki Myers | ... | Dafna Ben Bashat
  • Special Issue
  • - Volume 2015
  • - Article ID 389520
  • - Research Article

The Morphofunctional Effect of the Transplantation of Bone Marrow Stromal Cells and Predegenerated Peripheral Nerve in Chronic Paraplegic Rat Model via Spinal Cord Transection

Vinnitsa Buzoianu-Anguiano | Sandra Orozco-Suárez | ... | Israel Grijalva
  • Special Issue
  • - Volume 2015
  • - Article ID 389531
  • - Clinical Study

Cortical Reorganization Is Associated with Surgical Decompression of Cervical Spondylotic Myelopathy

Andrew Green | Priscilia W. T. Cheong | ... | Yew Long Lo
  • Special Issue
  • - Volume 2015
  • - Article ID 503079
  • - Research Article

Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine

R. Brunkhorst | F. Friedlaender | ... | W. Pfeilschifter
  • Special Issue
  • - Volume 2015
  • - Article ID 823185
  • - Research Article

The Plasticity of Brain Gray Matter and White Matter following Lower Limb Amputation

Guangyao Jiang | Xuntao Yin | ... | Jian Wang
Neural Plasticity
 Journal metrics
Acceptance rate53%
Submission to final decision58 days
Acceptance to publication37 days
CiteScore6.900
Impact Factor3.093
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