SOD1 Transcriptional and Posttranscriptional Regulation and Its Potential Implications in ALS

Figure 1

Genomic organization of human SOD1 gene. The size of exons and introns, in base pairs, is shown in association with each fragment. The 5′ flanking region is expanded, and the transcription factors, interacting with the corresponding DNA regulatory elements, are shown at the bottom. The transcription start site is depicted as an arrow at position +1.