DTI and MR Volumetry of Hippocampus-PC/PCC Circuit: In Search of Early Micro- and Macrostructural Signs of Alzheimers's Disease

<table>Nonparametric statistical results of voxelwise analysis in SPM8, on probability distribution of the tract connecting hippocampus with PC/PCC in MCI patients, AD patients, and healthy controls (<svg height="11.375" id="M44" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 50.549999 11.375" width="50.549999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><use xlink:href="#x1D443"></use></g><g transform="matrix(.017,-0,0,-.017,15.582,11.112)"><use xlink:href="#x3C"></use></g><g transform="matrix(.017,-0,0,-.017,30.286,11.112)"><use xlink:href="#x2E"></use></g><g transform="matrix(.017,-0,0,-.017,34.162,11.112)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,42.321,11.112)"><use xlink:href="#x35"></use></g>
</svg>, FWE correction). The red regions represent the areas in which tract connecting hippocampus with PC/PCC is significantly degenerated in AD patients compared to CTRL. The blue regions represent the areas in which this tract is significantly degenerated in MCI patients compared to CTRL.</table>

Neurology Research International

fig4

Figure 4

Figure 4: DTI and MR Volumetry of Hippocampus-PC/PCC Circuit: In Search of Early Micro- and Macrostructural Signs of Alzheimers's Disease 