Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia

Table 3

Talairach labels for networks detected by SBM .Voxel above a threshold of |𝑍|>3.0 were converted from Montreal Neurological Institute (MNI) coordinates to Talairach coordinates and entered into a database to assign anatomic labels for the left (L) and right (R) hemispheres. The concentration of voxels in each area is provided in cubic centimeters (cc). The areas with volume above 1.0 are listed. Within each area, the maximum 𝑍 value and its coordinate are provided.

	Brodmann area	L/R volume (cc)	L/R random effects: max𝑍(𝑥,𝑦,𝑧)
Angle source 1:
Thalamus		13.2/12.5	16.7(−10,−13,12)/15.7(10,−15,12)
Lingual gyrus	18, 17, 19	3.5/11.4	5.9(−16,−80,−2)/11.2(13,−83,−3)
Cuneus	18, 17, 30, 19, 7, 23	8.6/11.7	7.4(0,−84,17)/10.4(7,−85,11)
Inferior and middle occipital gyri	17, 19, 18, 37	8.0/5.4	7.4(−39,−73,−5)/9.3(13,−88,−7)
Culmen		1.3/1.7	7.8(−3,−32,−5)/8.2(3,−34,−5)
Precuneus	31, 7, 19	1.7/4.5	5.8(−9,−72,23)/7.4(6,−73,22)
Caudate		1.3/0.4	6.6(−7,−2,15)/4.7(18,−24,18)
Superior, Inferior and middle frontal gyri	6, 47, 11, 9, 10	2.8/7.3	6.3(−19,−11,72)/5.4(25,21,−16)
Parahippocampal gyrus	27, 35, 30, 36, 28	0.9/2.2	4.8(−15,−29,−6)/6.0(12,−34,−1)
Middle temporal gyrus	22, 21, 19, 39	1.3/1.7	4.6(−52,−41,5)/5.3(49,−38,1)
Fusiform gyrus	19, 18, 37	1.3/1.1	4.5(−39,−73,−10)/3.6(27,−84,−12)
Postcentral gyrus	3, 5	0.6/1.1	3.2(−27,−39,66)/4.1(33,−31,69)
Angle source 2:
Postcentral gyrus	3, 1, 2, 43, 40, 5, 7	11.0/21.2	9.9(−53,−17,60)/15.5(55,−15,55)
Precentral gyrus	6, 4, 43, 44, 9	8.0/22.5	5.9(−53,−7,56)/12.3(52,−10,57)
Inferior and middle frontal gyri	9, 45, 44, 46, 13, 6, 8	6.3/23.1	7.4(−45,24,17)/8.2(58,4,23)
Inferior and superior parietal lobules	40, 7	5.8/12.9	6.1(−53,−31,43)/5.4(49,−39,39)
Middle and inferior occipital gyri	18, 37, 19	3.3/1.3	6.0(−27,−103,7)/4.8(39,−68,2)
Insula	13	0.2/0.4	4.9(−39,24,17)/5.9(40,23,17)
Supramarginal gyrus	40	0.9/2.8	4.6(−48,−49,31)/5.9(46,−43,37)
Cuneus	18, 19	2.4/na	5.7(−16,−104,11)/na
Posterior cingulate	23, 30, 29	2.2/0.9	5.6(0,−38,23)/4.7(4,−35,25)
Inferior and superior temporal gyri	19, 20, 37, 22, 42, 39, 41	3.5/4.3	5.1(−48,−63,−4)/4.7(40,−66,−3)
Fusiform gyrus	37, 19, 20, 18	1.7/1.1	4.9(−40,−54,−7)/4.1(42,−62,−7)
Superior frontal gyrus	8, 11	na/1.7	na/4.4(40,18,47)
Orbital gyrus	11, 47	0.9/1.9	3.5(−16,23,−29)/4.0(7,45,−30)
Angle source 3:
Cuneus	19, 18, 7	13.4/11.9	16.9(−19,−90,39)/13.2(16,−90,36)
Precuneus	19, 7, 31, 39	16.2/14.9	16.2(−21,−85,43)/15.4(16,−88,42)
Superior parietal lobule	7, 5	11.2/10.2	11.7(−19,−69,57)/9.0(15,−70,59)
Middle and superior occipital gyri	18, 19	6.5/3.3	10.5(−21,−98,24)/7.1(27,−96,24)
Inferior and superior temporal gyri	20, 22, 13, 39	5.4/2.2	8.1(−50,−23,−33)/5.7(52,−26,−31)
Superior frontal gyrus	11, 10	2.8/1.5	8.0(−7,58,−27)/4.4(22,70,−1)
Rectal gyrus	11	1.7/0.9	7.2(−1,23,−29)/6.2(4,25,−29)
Fusiform gyrus	20	2.6/1.5	6.3(−59,−19,−29)0𝑥020445.8(58,−26,−30)
Postcentral gyrus	7, 3, 5, 2, 4	5.8/1.5	5.4(−15,−55,65)/4.3(4,−40,66)
Inferior parietal lobule	7, 39, 40	2.2/na	4.9(−39,−66,45)/na
Angle source 4:
Precentral gyrus	6, 4, 44, 9	20.7/6.0	19.3(−39,−7,61)/5.4(36,−9,57)
Middle and superior frontal gyri	6, 8, 9, 11, 46, 10	26.4/6.5	15.7(−33,−7,61)/7.9(28,24,38)
Inferior parietal lobule	40	7.1/4.1	11.1(−39,−34,39)/8.4(33,−39,39)
Postcentral gyrus	3, 5, 2, 1	8.0/0.4	10.2(−48,−19,64)/3.1(48,−30,35)
Insula	13	0.4/2.6	5.6(−34,21,9)/6.7(40,18,9)
Inferior and medial frontal gyri	13, 44, 45, 9, 47, 6, 25	4.8/3.6	6.7(−40,21,7)/6.0(45,15,12)
Precuneus	7, 31, 19	1.7/0.4	4.9(−22,−81,50)/5.9(30,−43,42)
Inferior semi-lunar lobule		3.0/na	5.9(−45,−71,−46)/na
Cerebellar tonsil		1.7/na	5.6(−48,−65,−46)/na
Superior parietal lobule	7	1.3/na	5.2(−27,−69,46)/na
cuneus	18, 17	1.1/1.1	4.5(−1,−103,4)/4.6(1,−103,9)
Angle source 5:
Middle and superior frontal gyri	9, 10, 8, 46, 6, 11	39.6/46.9	10.0(−39,25,32)/11.5(34,33,25)
Precentral gyrus	9	0.6/1.3	9.0(−39,21,36)/11.1(36,22,35)
Cuneus	17, 18, 23, 30, 19	1.9/9.3	4.1(−13,−93,35)/7.3(18,−72,9)
Medial and inferior frontal gyri	9, 8, 11, 6, 47, 48	5.0/7.6	4.5(−1,47,42)/6.2(9,50,36)
Rectal gyrus	11	1.5/1.5	5.0(−3,29,−29)/5.9(3,29,−28)
Lingual gyrus	18, 17	0.2/2.2	3.5(−25,−59,8)/5.7(7,−102,−9)
Inferior parietal lobule	40	2.2/na	5.6(−50,−39,28)/na
Orbital gyrus	11	0.6/1.9	4.0(−3,35,−31)/4.9(9,51,−28)
Inferior temporal gyrus	20, 21	1.1/0.4	4.1(−61,−23,−17)/3.3(50,−11,−20)
Angle source 6:
Lingual gyrus	17, 18, 19	10.2/0.9	12.8(−15,−86,−2)/4.6(30,−73,−4)
Middle and inferior frontal gyri	9, 46, 10, 11, 6, 8, 47, 45	8.4/10.1	10.6(−36,13,28)/11.6(34,14,27)
Orbital gyrus	11, 47	0.2/4.1	3.1(−18,25,−23)/10.2(15,37,−22)
Cuneus	17, 18, 19, 30, 23, 7	13.8/1.5	9.6(−12,−91,6)/4.3(16,−71,9)
Parahippocampal gyrus	36, 35, 28, Hippocampus, 30, Amygdala	4.3/2.4	9.3(−25,−20,−28)/7.0(21,−22,−29)
Precentral gyrus	9, 6, 4	1.7/2.6	7.5(−33,9,31)/9.1(36,13,32)
Rectal gyrus	11	na/1.9	na/8.1(10,40,−20)
Middle occipital gyrus	18, 19	3.7/0.9	8.0(−12,−90,13)/5.6(33,−76,15)
Middle and superior temporal gyri	39, 19, 21, 22, 37, 13, 41, 42	3.9/4.1	7.8(−34,−72,17)/6.0(56,−39,13)
Superior and medial frontal gyri	10, 11, 6, 25, 9	2.4/4.8	7.5(−27,48,2)/5.9(24,48,3)
Cerebellar tonsil		16.4/6.7	7.5(−28,−47,−37)/6.4(25,−38,−31)
Cerebellar vermis		3.2/3.0	7.3(−21,−18,−31)/7.6(24,−26,−31)
Insula	13	0.9/1.1	7.3(−37,18,18)/4.7(50,−39,13)
Cingulate gyrus	24, 31	1.7/na	5.7(−10,−2,39)/na
Precuneus	31, 7, 19	0.9/1.1	4.1(−25,−62,34)/4.5(28,−76,19)
Posterior cingulate	30	1.1/0.6	4.5(−28,−71,16)/3.8(18,−65,7)
Postcentral gyrus	3, 5, 1, 2	1.7/1.1	4.4(−42,−23,67)/3.6(71,−16,26)
Inferior parietal lobule	40	1.5/0.2	4.2(−42,−39,38)/3.2(52,−48,54)
Thalamus		1.3/na	4.1(−16,−27,7)/na
Power source:
Insula	13, 40, 41, 22	8.2/10.8	11.0(−45,7,0)/13.8(43,10,−7)
Superior and transverse temporal gyri	22, 38, 13, 41, 42	17.0/15.7	13.8(−46,7,−5)/13.2(45,4,−5)
Inferior and medial frontal gyri	47, 13, 45, 9, 11, 10, 6, 25, 8	20.1/12.1	12.6(−46,13,−4)/12.2(42,16,−8)
Precentral and postcentral gyri	6, 13, 44, 43, 40	5.6/2.4	12.2(−46,−7,6)/5.5(53,−6,6)
Anterior cingulate and cingulate gyrus	32, 24, 25, 10	11.0/3.9	9.0(−1,42,2)/6.1(4,44,3)
Claustrum		0.9/1.7	5.2(−37,−10,7)/5.8(37,−13,8)
Parahippocampal gyrus	30, 35, 34, 27, 28, 36, Amygdala	3.5/3.9	5.4(−15,−32,−5)/5.4(13,−34,−3)
Inferior parietal lobule	40	1.1/0.2	5.0(−61,−24,23)/3.1(55,−31,22)
Thalamus		1.9/0.6	4.7(0,−17,6)/3.2(15,−33,2)
Cerebellar vermis		2.8/3.2	4.4(−21,−34,−13)/5.9(24,5,−22)