Protective Effect of PPARγ Agonists on Cerebellar Tissues Oxidative Damage in Hypothyroid Rats

Figure 2

The effects of PTU, Vit E, pioglitazone, and rosiglitazone on cerebellar MDA concentrations. Data are presented as mean ± SEM; . and versus group I; and versus group II; versus group III; compared to group IV; and compared to group VI. The data from different treatment groups were compared by using one way ANOVA followed by post hoc LSD test. Group I (control), the animals received drinking water; group II, the animals received 0.05% propylthiouracil (PTU) in drinking water; besides PTU, the animals in groups III, IV, V, VI, and VII were injected with 20 mg/kg vitamin E (vit E), 10 or 20 mg/kg pioglitazone, and 2 or 4 mg/kg rosiglitazone, respectively.