Research Article

Leptomeningeal Contrast Enhancement Is Associated with Disability Progression and Grey Matter Atrophy in Multiple Sclerosis

Table 1

Cohort demographic characteristics.

Number of participants54
(%) female34 (63%)
Median age at the time of MRI, years (IQR)42 (22.5)
Median disease duration, months (IQR)86 (149.05)
Median EDSS (25th, 75th percentile)4 (2.5, 6.0)
Disease course at enrollment, (%)
 (i) RRMS36 (77%)
 (ii) SPMS12 (22%)
 (iii) PPMS6 (11%)

MRI: magnetic resonance imaging; EDSS: Expanded Disability Status Scale; MSSS: Multiple Sclerosis Severity Score; RRMS: relapsing-remitting multiple sclerosis, SPMS: secondary progressive multiple sclerosis, PPMS: primary progressive multiple sclerosis.