Neurology Research International / 2018 / Article / Tab 2

Clinical Study

The Effect of Hyperbaric Oxygen Therapy on Functional Impairments Caused by Ischemic Stroke

Table 2

Effect of HBOT on functional impairments: means and effect size.

DomainBaseline  
(mean+ SD)
HBOT  
(mean+ SD)
Paired t test  
B1,2 vs T1,2
Effect Size

Cognitive
 CVLT-II49.6 + 10.459 + 11.90.011.56
 GP39.4 + 9.544.5 + 15.50.130.38
 Trails A34.1 + 8.639.2 + 7.40.100.79
 Trails B37.9 + 12.640.8 + 8.40.510.28
 COWAT38.1 + 8.341.7 + 9.60.090.81
 SF - animals42.9 + 10.844.1 + 15.20.760.13
 WASI44.1 + 12.544.6 + 9.50.780.11
 WMS10.4 + 0.912.2 + 2.10.031.11
 DKEFS9.7 + 2.911.1 + 1.60.110.76

Physical
 UEFM37.7 + 23.142.0 + 22.20.030.85
 Berg48.7 + 9.750.7 + 9.80.260.5
 Gait Velocity68.7 + 8.783.5 + 8.40.011.5
 Step length3.79 + 1.52.36 + 1.90.33-0.39
 Step time0.05 + 0.060.04+ 0.020.36-0.36

Quality of Life
 BDI14.5 + 10.810.0 + 7.70.09-0.82
 SIS Global52.1 + 26.561.7 +18.40.040.73
 SIS Strength49.0 + 13.649.5 + 13.50.750.04
 SIS Memory85.9+ 17.790.9 + 12.80.590.34
 SIS Emotional74.4 + 15.882.6 + 13.80.140.54
 Communication84.8 + 20.186.8 + 12.40.650.28
 SIS ADL’s72.3 + 19.372.5 + 19.90.950.02
 SIS mobility71.2 + 10.978.3 + 15.80.320.38
 Hand Function58.9 + 32.560.6 + 31.80.570.23
 Participation50.6 + 13.864.6 + 30.10.110.54
 Physical Comp.56.0 + 25.861.1 + 24.40.090.81
 Sleep41.2 + 7.748.5 + 9.80.041.17
 Satisfaction46.2 + 6.153.8 + 12.20.160.68

Biomarkers
 NSE2.2 + 0.42.9 + 0.50.0052.1
 GFAP10.1 + 18.917.3 + 27.50.130.74
 IL-66.3 + 6.83.9 + 4.90.05-1.0
 TNF-a7.0 + 2.04.7 + 1.40.01-1.5