| | Domain | B1 versus B2 | B1,2 vs T1,2 | T1,2 vs Off and Follow-up | Off vs Follow-up |
| | Cognitive | | | | | | CVLT-II | F(1,5)=0.13, p=0.74 | F(1,5)=15.7, p=0.01 | F(1,4)=0.13, p=0.74 | F(1,4)=2.78, p=0.19 | | Trails A | F(1,5)=0.01, p=0.77 | F(1,5)=3.9, p=0.10 | F(1,4)=1.27, p=0.34 | F(1,4)=2.95, p=0.18 | | COWAT | F(1,5)=2.59, p=0.17 | F(1,5)=4.0, p=0.09 | F(1,4)=0.31, p=0.61 | F(1,4)=0.003, p=0.96 | | WMS | F(1,5)=0.29, p=0.61 | F(1,5)=7.74, p=0.03 | F(1,4)=1.0, p=0.39 | F(1,4)=1.0, p=0.39 | | DKEFS | F(1,5)=0.11, p=0.78 | F(1,5)=3.6, p=0.11 | F(1,4)=0.07, p=0.81 | F(1,4)=0.11, p=0.76 |
| | Physical | | | | | | UEFM | F(1,5)=0.65, p=0.46 | F(1,5)=9.6, p=0.03 | F(1,4)=6.5, p=0.06 | F(1,4)=0.24, p=0.64 | | Gait Velocity | F(1,4)=3.7, p=0.12 | F(1,4)=24.9, p=0.01 | F(1,3)=0.13, p=0.75 | F(1,3)=0.25, p=0.65 |
| | Quality of Life | | | | | | BDI | F(1,5)=0.16, p=0.71 | F(1,5)=6.7, p=0.09 | F(1,4)=1.4, p=0.32 | F(1,4)=0.66, p=0.48 | | SIS Global | F(1,5)=8.4, p=0.03 | F(1,5)=7.2, p=0.04 | F(1,4)=2.0, p=0.23 | F(1,4)=1.67, p=0.27 | | SIS Emotional | F(1,5)=0.56, p=0.28 | F(1,5)=3.0, p=0.14 | F(1,4)=0.83, p=0.41 | F(1,4)=0.51, p=0.51 | | SIS Participation | F(1,5)=0.005, p=0.9 | F(1,5)=3.7, p=0.11 | F(1,4)=0.56, p=0.50 | F(1,4)=0.08, p=0.80 | | SIS Physical | F(1,5)=2.8, p=0.17 | F(1,5)=4.2, p=0.09 | F(1,4)=0.96, p=0.38 | F(1,4)=1.0, p=0.36 | | Sleep | F(1,5)=6.5, p=0.06 | F(1,5)=8.2, p=0.04 | F(1,4)=1.5, p=0.28 | F(1,4)=0.001, p=0.97 | | Satisfaction | F(1,5)=0.06, p=0.82 | F(1,5)=2.7, p=0.16 | F(1,4)=6.8, p=0.06 | F(1,4)=0.11, p=0.75 |
| | Biomarkers | | | | | | NSE | F(1,5)=0.01, p=0.85 | F(1,5)=22.8, p=0.005 | F(1,4)=16.0, p=0.01 | F(1,4)=0.24, p=0.64 | | GFAP | F(1,5)=0.06, p=0.81 | F(1,5)=3.27, p=0.13 | F(1,4)=2.97, p=0.16 | F(1,4)=0.13, p=0.74 | | IL-6 | F(1,5)=0.02, p=0.89 | F(1,5)=6.0, p=0.05 | F(1,4)=5.3, p=0.08 | F(1,4)=1.1, p=0.36 | | TNF-a | F(1,5)=0.04, p=0.85 | F(1,5)=14.2, p=0.013 | F(1,4)=18.4, p=0.01 | F(1,4)=0.34, p=0.59 |
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