Efficacy of High-Dose and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcomes in Patient with Acute Ischemic Stroke: A Randomized, Double-Blind, Parallel, Controlled Trial

Table 4

Compare serum sLOX-1 and NO levels in patient with acute ischemic stroke at 0 days and 90 days after simvastatin therapy.

Parameter	Simvastatin 10 mg (N = 34); Mean ± SD		value	Simvastatin 40 mg (N = 31); Mean ± SD		value
	Day 0	Day 90		Day 0	Day 90
sLOX-1; levels (ng/ml)	1.42 ± 0.49	1.19 ± 0.47	<0.001	1.72 ± 0.55	0.98 ± 0.37	<0.001
NO levels (µmol/l)	55.06 ± 9.26	49.28 ± 7.21	0.03	51.72 ± 8.83	46.59 ± 9.36	0.005