Table 1

PatientAge/sexEtiologyOther AEDsOrder of IV LCMLoading/maintenance dose (MKDose)% seizure reduction in 24 hrEfficacy (% seizure reduction)Side effect

110 YTraumatic brain injuryLEV, CZP, VPA, TPM310/6.685.71No changeNo
212 MLennox-Gastaut syndromeLEV, DZP, CLB, TPM, PPN210/575>50%bradycardia
315 YAnti NMDAR encephalitisLEV, TPM16.7/2.2100Seizure freeNo
49 Mneuronal ceroid lipofusinosisLEV, CZP, VPA, TPM, LTG38/585>50%No
59 Yfocal epilepsy of unknown etiology LEV, PHT44.7/4.7100No changeNo
614 Yfocal epilepsy of unknown etiology LEV, VPA, TPM35/2.5100>50%No
714 YLennox-Gastaut syndromeLEV, TPM, CLB, PB29/4.590>75%No
810 Yfocal epilepsy of unknown etiologyVPA, TPM, CBZ29/4.5100>75%No
97 YSchizencephalyTPM, DZP, PB310/566.67>75%No
1016 Yfocal epilepsy of unknown etiologyPHT, TPM, CZP210/5100No changeNo
118 MLennox-Gastaut syndromeLEV, PPN, LTG, PB28.7/5.271.42>75%No

AEDs: antiepileptic drugs; IV: Intravenous; LCM: lacosamide; LEV: levetiracetam; CZP: clonazepam; VPA: valproic acid; TPM: topiramate; DZP: diazepam; CLB: clobazam; PPN: perampanel; LTG: lamotrigine; PHT: phenytoin; PB: phenobarbital; CBZ: carbamazepine.