Neurology Research International

Multimodal MRI in Neurodegenerative Disorders


Publishing date
15 Oct 2011
Status
Published
Submission deadline
15 Apr 2011

Lead Editor

1Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Germaneto, 88100 Catanzaro, Italy

2Department of Radiology, I.R.C.C.S. Foundation Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy

3INSERM U825, Université Paul-Sabatier, Toulouse, France


Multimodal MRI in Neurodegenerative Disorders

Description

Magnetic Resonance Imaging (MRI) is increasingly considered as a potential provider of markers useful for early diagnosis in patients with neurological disorders. However, while some neurological diseases such as Alzheimer's disease or multiple sclerosis are associated with evident brain tissue alterations (such as gray matter volume loss and white matter demyelination), other disorders such as Parkinson's disease, essential tremor, and mild cognitive impairment are generally associated with negative evidence from conventional neuroradiology. Nevertheless, during last years, several research groups, using advanced multimodal neuroimaging, demonstrated the existence of numerous underlying brain abnormalities that could predict or characterize the onset of these diseases. The concomitant improvements in computational tools and in magnetic resonance image quality have triggered a large renewal of interest in this field of study. The main focus of this special issue will be on the new findings revealed by advanced brain imaging and analysis methods such as Voxel-based and Tensor-based Morphometry, Cortical Thickness analysis, diffusion tensor imaging, quantitative relaxometry, resting state connectivity, applied to the study of neurodegenerative disorders. The main goal is to describe the novel markers derived from MRI which are able to better define the pathophysiological correlates of these diseases such as macro-/microstructural volumetric changes, quantification of mineral accumulation, and alteration of well-defined functional networks. Main topics include, but are not limited to:

  • Combined application of VBM and cortical thickness in neurological disorders
  • Microstructural changes as revealed by diffusion analysis in movement disorders
  • Quantitative relaxometry as a possible early marker of Parkinson's disease
  • Individual patient diagnosis via pattern classification of MRI in dementia
  • Altered resting-state functional connectivity in neurodegenerative disorders
  • Combination of multiple MRI methods to differentiate the profile of normal aging changes from regional alterations induced by neurodegeneration

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/nri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 287891
  • - Editorial

Multimodal MRI in Neurodegenerative Disorders

Antonio Cerasa | Andrea Cherubini | Patrice Peran
  • Special Issue
  • - Volume 2012
  • - Article ID 735249
  • - Research Article

Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia

Lai Xu | Tülay Adali | ... | Vince D. Calhoun
  • Special Issue
  • - Volume 2012
  • - Article ID 907409
  • - Review Article

Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease

Ai-Ling Lin | Angela R. Laird | ... | Jia-Hong Gao
  • Special Issue
  • - Volume 2012
  • - Article ID 718150
  • - Research Article

A Pilot Study of Quantitative MRI Measurements of Ventricular Volume and Cortical Atrophy for the Differential Diagnosis of Normal Pressure Hydrocephalus

Dana W. Moore | Ilhami Kovanlikaya | ... | Norman R. Relkin
  • Special Issue
  • - Volume 2012
  • - Article ID 197438
  • - Review Article

MRI Findings in Neuroferritinopathy

Emiko Ohta | Yoshihisa Takiyama
  • Special Issue
  • - Volume 2012
  • - Article ID 719056
  • - Review Article

Understanding the Pathophysiology of Alzheimer's Disease and Mild Cognitive Impairment: A Mini Review on fMRI and ERP Studies

Takao Yamasaki | Hiroyuki Muranaka | ... | Shozo Tobimatsu
  • Special Issue
  • - Volume 2012
  • - Article ID 517876
  • - Research Article

DTI and MR Volumetry of Hippocampus-PC/PCC Circuit: In Search of Early Micro- and Macrostructural Signs of Alzheimers's Disease

F. Palesi | P. Vitali | ... | S. Bastianello
Neurology Research International
 Journal metrics
Acceptance rate19%
Submission to final decision58 days
Acceptance to publication25 days
CiteScore1.800
Impact Factor-
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