Development and Evaluation of Evidence-Informed Clinical Nursing Protocols for Remote Assessment, Triage and Support of Cancer Treatment-Induced Symptoms

Table 3

Characteristics of guidelines about diarrhea (𝑛=7).

Author (Year)	Country	Defines symptom	Criteria to assess symptom	Risk stratification	Self-care to manage symptom	Followup for ongoing monitoring	Other recommendations in guideline	Rigour score (raters would recommend)
Major et al. (2004) [31]	Canada	—	Limited	NCI-CTC grade; 0 to 4	OTC medications	Reassess within 24 hours	Use of prescribed medication	86 (4/4)
Rubenstein et al./Keefe et al. (2004/2007) [32, 44]	USA; Australia	—	Limited	NCI-CTC grade; 0 to 4	OTC medications	—	Use of prescribed medication	82 (4/4)
Benson et al. (2004) [33]	USA	—	√	Uncomplicated versus complicated	Dietary and OTC medications	Reassess within 24 hours	Use of prescribed medications	73 (4/4)
ONS-PEP (2008) [36]	USA	√	√	Similar to complicated above	Dietary and OTC medications	—	Use of prescribed medications	48 (4/4)
BC Cancer Agency (2004) [34]	Canada	—	Limited	NCI-CTC grade 0 to 4	Dietary and OTC medications	Reassess within 24 hours	Use of prescribed medications	17 (2/4)
BC Cancer Agency (2008) [35]	Canada	√	√	Nonurgent, urgent, emergent	Dietary and OTC medications	Reassess within 24 hours	Use of prescribed medications	14 (2/4)
Cancer Care Ontario (2004) [37]	Canada	√	√	Nonurgent, urgent, emergent	Dietary	—	—	8 (2/4)

√: present in the guideline; —: none; OTC: over the counter; NCI-CTC: National Cancer Institute Common Terminology Criteria.