Research Letter
Synthesis and Biological Evaluation of 7-O-Modified Formononetin Derivatives
Table 2
Antimicrobial activity of the synthesized compounds.
| | Compounds | Minimum inhibitory concentrations MICs (μg/mL) | | Gram positive | Gram negative | | S. faecalis | S. aureus | B. subtilis | E. coli | P. aeruginosa | E. cloacae |
| | 1 | 3.12 | 25.00 | 50.00 | 50.00 | 25.00 | 50.00 | | 2a | 3.12 | 6.25 | 3.12 | 6.25 | 1.56 | 50.00 | | 2b | 3.12 | 50.00 | 25.00 | 6.25 | 25.00 | 1.56 | | 2c | 3.12 | 3.12 | 50.00 | 12.50 | 25.00 | 12.50 | | 3a | 3.12 | 6.25 | 50.00 | 3.12 | 3.12 | 25.00 | | 3b | 1.56 | 12.50 | 0.78 | 3.12 | 50.00 | 3.12 | | 3c | 3.12 | 6.25 | 6.25 | 25.00 | 6.25 | 3.12 | | 3d | 3.12 | 6.25 | 6.25 | 12.50 | 3.12 | 6.25 | | 3e | 3.12 | 1.56 | 50.00 | 25.00 | 25.00 | 6.25 | | 3f | 3.12 | 12.50 | 25.00 | 6.25 | 50.00 | 25.00 | | 4a | 3.12 | 3.12 | 50.00 | 6.25 | 50.00 | 50.00 | | 4b | 3.12 | 25.00 | 3.12 | 1.56 | 6.25 | 12.50 | | 4c | 3.12 | 12.50 | 25.00 | 6.25 | 6.25 | 12.50 | | 4d | 3.12 | 6.25 | 3.12 | 12.50 | 3.12 | 25.00 | | 4e | 3.12 | 3.12 | 50.00 | 1.56 | 50.00 | 50.00 | | 5a | 3.12 | 1.56 | 6.25 | 25.00 | 6.25 | 3.12 | | 5b | 3.12 | 12.50 | 1.56 | 25.00 | 50.00 | 50.00 | | 5c | 3.12 | 50.00 | 1.56 | 6.25 | 6.25 | 50.00 | | 5d | 3.12 | 50.00 | 25.00 | 6.25 | 3.12 | 6.25 | | 5e | 3.12 | 0.78 | 12.50 | 6.25 | 25.00 | 25.00 | | 5f | 3.12 | 25.00 | 50.00 | 50.00 | 3.12 | 1.56 |
| | Penicillin | 1.56 | 1.56 | 1.56 | 6.25 | 6.25 | 3.12 | | Kanamycin | 3.12 | 1.56 | 0.39 | 3.12 | 3.12 | 1.56 |
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