Table of Contents
Organic Chemistry International
Volume 2011, Article ID 514620, 7 pages
Research Article

Synthesis of β-Amino Carbonyl Compounds via the Iodine-Alumina Catalyzed Three-Component Coupling Reaction under Microwave Irradiation

Department of Chemistry, North Eastern Hill University, Mawlai Campus, Shillong 793022, India

Received 3 September 2010; Accepted 13 December 2010

Academic Editor: Bill Baker

Copyright © 2011 Mantu Rajbangshi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Iodine-alumina was employed as a catalyst in the coupling reactions of aldehydes, enolizable ketones, or 1,3-dicarbonyls with methyl carbamate or aromatic amines under microwave irradiation to afford β-amino carbonyl compounds in good-to-excellent yields. The key features of this environmentally friendly methodology are its operational simplicity, mild reaction conditions, and less reaction time.