Synthesis and Characterization of N1-Phenylhydrazine-1,2-bis(carbothioamide) and Its Evaluation for Antimicrobial, Antioxidant, and Brine Shrimp Lethality Bioassay
Table 2
Determination of LC50 values of the compound in Brine Shrimp Nauplii.
Compound
Conc. (μg/mL)
Log conc.
% mortality
Corrected %*
Probit
LC50 value from graph (μg/mL)
Vincristine sulfate
10
1.0
100
97.5
6.96
0.33
5.000
0.698
90
90
6.28
2.500
0.397
80
80
5.84
1.250
0.096
80
80
5.84
0.625
−0.204
60
60
5.25
0.313
−0.505
50
50
5.00
0.156
−0.806
40
40
4.75
0.078
−1.107
20
20
4.16
-Phenylhydrazine-1,2-bis (carbothioamide)
200
2.301
100
97.5
6.96
12.79
100
2.0
80
80
5.84
50
1.699
70
70
5.52
25
1.398
50
50
5.00
12.5
1.097
40
40
4.75
6.25
0.796
30
30
4.48
3.125
0.495
30
30
4.48
1.563
0.194
20
20
4.16
0.781
−0.107
10
10
3.72
orrected: for the 100% mortality: 100[()/], where = number of shrimps in each group.
