Synthesis of Pyrazine Substituted 1,3,4-Thiadiazole Derivatives and Their Anticonvulsant Activity

Table 1

Chemical structure and melting range of pyrazine substituted 1,3,4-thiadiazole derivatives 7(a–o).

Compound	R	Structure	M.p. (°C)
7a			244–246
7b			136–138
7c			170–172
7d			200–202
7e			138–140
7f			228–230
7g			260–262
7h			160–162
7i			220–222
7j			166–168
7k			252–254
7l			88–90
7m			226–228
7n			234–236
7o			170–172