Catalytic Synthesis of -Aminonitriles Using Nano Copper Ferrite under Green Conditions

Table 4

Synthesis of 2-(4-Nitrophenyl)-2-(phenylamino)acetonitrile (4i) in the presence of (nano copper ferrite (CuFe₂O₄) catalyst without AcOH) and various solvents at room temperature (solvent optimization).

Entry	Solvent	^aYield (%)
1	H2O	90.5
2	C2H5OH	51
3	DMF	73
4	DMSO	72.5
5	CHCl3	70
6	C6H5CH3	71
7	CH3OH	65
8	CH2Cl2	70.5
9	CCl4	77
10	C6H6	72
11	n-Hexane	64

aIsolated yields.