Glycerol Containing Triacetylborate Mediated Syntheses of Novel 2-Heterostyryl Benzimidazole Derivatives: A Green Approach

Table 2

Synthesis of 2-hetero/styryl-benzimidazoles 3(a–p) from cinnamic acids 2(a–h) and benzaldehydes 5(a–h).

S.; number	Product 3(a–p)	Method-1 (diamine + cinnamic acid)			Method-2 (2-MeBz + aldehydes)			M.P (°C)
		Time; (h)	Temp; (°C)	Yield; (%)	Time; (h)	Temp; (°C)	Yield; (%)
1.		4	160	90	6	160	88	205 (202) [16]
2.		3.5	150	86	6	160	92	114-115 (113) [15]
3.		3.5	160	90	6	160	90	221–223 (223-224) [16]
4.		4	150	90	6	160	92	>240 (262-263) [16]
5.		5	160	85	6	160	88	210–212 (214–216) [16]
6.		5	160	78	6	150	85	200–204
7.		5	150	92	5	150	94	218–220
8.		5	160	92	5	150	90	198–200
9.		5	160	90	6	160	88	202–204
10.		5	160	84	6	160	90	178–180
11.		5	160	90	6	160	90	130–132
12.		5	150	92	6	160	86	210–212
13.		5	150	88	6	160	86	198–200
14.		5	160	84	5	160	88	>240
15.		5	160	80	5	150	82	100–102
16.		5	150	78	5	150	80	108–110