Table of Contents
Organic Chemistry International
Volume 2014, Article ID 715091, 6 pages
Research Article

Green Chemistry: New Synthesis of Substituted Chromenes and Benzochromenes via Three-Component Reaction Utilizing Rochelle Salt as Novel Green Catalyst

Department of Chemistry, Faculty of Science, South Valley University, Qena 83523, Egypt

Received 31 October 2013; Accepted 14 December 2013; Published 30 January 2014

Academic Editor: Ramadan A. Mekheimer

Copyright © 2014 Awatef Mohamed El-Maghraby. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Substituted 2-amino-4-aryl-7-hydroxy-4H-chromene-3-carbonitriles (6), 2-amino-4-aryl-4H-benzo[h]chromene-3-carbonitriles (7), and 3-amino-1-aryl-1H-benzo[f]chromenes-2-carbonitriles (8) were prepared, in good yields, via one-pot three-component reactions of aromatic aldehydes (1), malononitrile (2), and resorcinol (3) or α-naphthol (4) or β-naphthol (5) in refluxing ethanol or water in the presence of Rochelle salt as novel green heterogeneous and reusable catalyst.