Obstetrics and Gynecology International / 2009 / Article / Tab 3

Clinical Study

Recombinant Activated Factor VII (rFVIIa) in the Management of Major Obstetric Haemorrhage: A Case Series and a Proposed Guideline for Use

Table 3

Coagulation parameters before and after the administration of rFVIIa for major obstetric haemorrhage. Normal ranges: Prothrombin time 10–13 seconds; Activated partial thromboplastin time 25–37 seconds; Fibrinogen 2.1–4.8 seconds.

Pt no.Prothrombin timeActivated partialPlatelet countFibrinogen
(seconds)thromboplastin time (seconds)( 109/L)(g/L)
PrePostPrePostPrePostPrePost

1149303093961.71.5
221134933106851.42.6
3161052291291030.92.4
41510342589930.91.9
5161164571601251.31.7
61811603168480.41.4
72912160936220.60.9
81510343748451.52.1
915939308911922.1
10159603064690.93.6
11159503776620.90.8
121310503535572.12.3
13142831150308284.11.3
149.26.81014151341.93.36
1516.410.62126.5327882.62

Median1510503389691.42.0

P-values*0.0070.0250.1880.073

*Wilcoxon signed-rank test is shown.

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