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Obstetrics and Gynecology International
Volume 2009, Article ID 397079, 4 pages
Research Article

Evaluation of the Risk of Spreading Endometrial Cell by Hysteroscopy: A Prospective Longitudinal Study

1Departamento de Obstetrícia e Ginecologia, Hospital do Servidor Publico Estadual, “Francisco Morato de Oliveira”, Rua Pedro de Toledo 1800, 04039-901 São Paulo, SP, Brazil
2School of Medicine, University of São Paulo, São Paulo, SP, Brazil

Received 23 November 2008; Accepted 27 February 2009

Academic Editor: John J. Sciarra

Copyright © 2009 Rievani de Sousa Damião et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The aim was to assess the intraperitoneal spread of endometrial cells during hysteroscopy. Study Design. Seventy-six women were submitted to a hysteroscopy with C O 2 under a low pressure. Group 1 had not previous diagnosis of endometrial cancer, and group 2 had previous diagnosis of endometrial cancer (stage I-92.3%). Two peritoneal washing samples were taken before (PW1) and immediately after (PW2) the procedure. The dissemination for the peritoneal cavity was defined by the presence of endometrial cells in the PW2; such cells should be absent in WP1. Results. Four patients were excluded for presenting endometrial cells in PW1. In the 72 patients left, there was no passage of cells for the peritoneal cavity. In group 1, 88% presented secretory endometrial phase with correlation of 80% between hysteroscopy and biopsy. Conclusion. Hysteroscopy performed under a low pressure of C O 2 does not cause spreading of endometrial cells into the peritoneal cavity.