A Randomized Controlled Trial of Misoprostol and Sulprostone to End Pregnancy after Fetal Death

Table 4

Women’s assessment of the treatments and their side effects.

Outcome*	Misoprostol		Sulprostone
	(𝑛=70)		(𝑛=69)
	𝑛	%	𝑛	%
Nausea
None	44	62.9	41	59.4
All nausea	23	32.9	25	39.1
Light,	14	20.0	17	24.6
Moderate	2	2.9	6	8.7
Severe	7	10.0	2	2.9
Not reported	3	4.3	3	4.3
Vomiting
None	50	71.4	49	71.0
All vomiting	17	24.3	17	24.6
Only once	5	7.1	6	8.7
Several episodes	11	15.7	11	15.9
Not reported	4	5.7	3	4.3
Diarrhea
None	56	80.0	56	81.2
All diarrhea	11	15.7	10	14.5
Light,	6	8.6	7	10.1
Moderate	4	5.7	1	1.4
Severe	1	1.4	2	2.9
Not reported	3	4.3	3	4.3
Pain score (range 0 to 10)
Median (interquartile range)	5 (3–7)		5 (2–7)
Women’s perception of the duration of induction
Too long	10	14.3	14	20.3
Not too long	26	37.1	26	37.7
Uncertain	31	44.3	26	37.7
Not answered	3	4.3	3	4.3
Women’s opinion on restriction of movement *
Felt no restriction	40	57.1	22	31.9
Any restriction	24	34.3	44	63.8
Some restriction	21	30.0	36	52.2
Too restricted	3	4.3	8	11.6
Not answered	6	8.6	3	4.3
Women’s opinion on the acceptability of the procedure
Very acceptable	34	48.6	23	33.3
Acceptable	24	34.3	39	56.5
Poor acceptability	7	10.0	4	5.8
Not answered	5	7.1	3	4.3
Women’s overall satisfaction
Very satisfied	50	71.4	50	72.5
Satisfied	14	20.0	11	15.9
Little or not at all	2	2.9	3	4.3
Not answered	4	5.7	5	7.2
Would have preferred the other method
Yes	3	4.3	6	8.7
No	39	55.7	30	43.5
Do not know	23	32.9	30	43.5
Not answered	5	7.1	3	4.3

*There was no statistical difference in outcome between the two groups except for restriction of movement (Chi square test; 𝑃<.005).