Obstetrics and Gynecology International / 2009 / Article / Tab 1

Review Article

The Potential Use of Intrauterine Insemination as a Basic Option for Infertility: A Review for Technology-Limited Medical Settings

Table 1

Motile sperm concentration, normal morphology, and IUI outcome.

Author Year Design (prospective or retrospective) Number of infertile patientsNumber of insemination cycles IMSC (million) Normal morphology IUI outcome Total motile sperm count*10/6 (before wash)

Ombelet et al. 1997 Retrospective 373 792 <1 <4% 0% CF
<1 >4% 7.8%
>1 >4% 15%
Van Voorhis et al. 2001 Retrospective 1,039 3,479 PR 2.3% <10
PR 9% >10
Cohlen et al. 1998 Prospective 74 308 <1 PR 2.6%
>1 PR 11.2%
Wainer et al. 2004 Retrospective 889 2,564 <1 >30% PR 3.1%
2–5 PR 12%
Dodson & Haney 1991 Retrospective 371 808 <1 CF 0%
1–5 CF 17%
Horvath et al. 1989 Prospective 232 451 <1 CF 2.6%
>10 CF 11.6%
Berg et al. 1997 Retrospective 902 3,037 0.8–1.2 PRcy 8.2%
>5 10%
Miller et al. 2002 Prospective 438 1,114 <10 CF 1%
10–20 CF 7.4%
>20 CF 12.4%
Irianni et al. 1993 Retrospective 129 208 >4.7 PR 14%
Toner et al. 1994 Prospective 126 395 104 9% PRcy 9%
Lindheim et al. 1996 Retrospective 42 <4% PRcy 1%
>4% PRcy 19%
Montanaro Gauci et al. 1999 Retrospective 273 522 <4% PRcy 2.6%
5–14% 11%
>14% 24%
Shibahara et al. 2004 Prospective 160 682 >15% PRcy 15%
Hauser et al. 2001 Prospective 108 264 <4%4-PRcp 11%
14% 36%
>14% 50%
Lee et al. 2002 Prospective 209 244 <4% PRcy 3.8%
4–9% 18.5%
>9% 30%
Dickey et al.1999Retrospective1,8414,056<5% PRcy 0%
>5% 11%
Dickey et al.1999Retrospective1,8414,056PRcy 2.3%<5
8.5% >5

CF: Cycle fecundity; IMSC: Inseminated motile sperm count; PR: Overall pregnancy rate; PRcy: Pregnancy rate per cycle; PRcp: Pregnancy rate per couple.