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Obstetrics and Gynecology International
Volume 2009, Article ID 803062, 3 pages
Case Report

Recurrence of Mitotically Active Cellular Fibroma of the Ovary

1Département de Gynécologie, Hôpital Universitaire Erasme, route de Lennik 808, 1070 Brussels, Belgium
2Département de Pathologie, Hôpital Universitaire Erasme, route de Lennik 808, 1070 Brussels, Belgium

Received 24 September 2008; Accepted 9 December 2008

Academic Editor: Robert L. Coleman

Copyright © 2009 Dario Bucella et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. 10% of ovarian fibromatous tumours typically exhibit increased cellularity, mitotic activity, and less frequently nuclear atypia. Therefore, the classification within the group of fibromatous tumours may represent some difficulties, thus, one or several of these features should appear. Case. We introduce the clinical and pathologic features based on one case of recurrence of a mitotically active cellular ovarian fibroma (MACF) in the pararectal fossa. This recurrence took place six years after primary surgery. Macroscopically, the tumour was firm, fibrous, well delimited, yellow-white without gross necrosis. On microscopic examination, it was composed of a densely cellular proliferation of fibrolastic-like cells with bland nuclear features and arranged in a fascicular pattern. There was no sign of significant atypia or necrosis. Conclusion. Recently, this case is the first report of a recurrence of MACF, following primary surgery with no tumoral rupture or surgical difficulty. The clinical outcome of ovarian cellular fibromas (CFs) and MACFs is typically uneventful. This case, however, strongly suggests maintaining a long-term clinical follow-up even though the principal tumour was surgically treated without tumour rupture or in the absence of adherence or any surgical difficulty.