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Obstetrics and Gynecology International
Volume 2010, Article ID 743794, 6 pages
http://dx.doi.org/10.1155/2010/743794
Clinical Study

The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes

1Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195, USA
2Department of Biostatistics, University of Washington, Seattle, WA 98195, USA
3Department of Obstetrics and Gynecology, University of Rochester School of Medicine, Rochester, NY 14642, USA
4Department of Radiation Oncology, University of Washington, Seattle, WA 98195, USA

Received 9 December 2009; Revised 1 February 2010; Accepted 10 February 2010

Academic Editor: Bradley J. Monk

Copyright © 2010 Heidi J. Gray et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, R. Siegel, E. Ward et al., “Cancer statistics, 2008,” CA Cancer Journal for Clinicians, vol. 58, no. 2, pp. 71–96, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. F. Landoni, A. Maneo, A. Colombo et al., “Randomised study of radical surgery versus radiotherapy for stage IB-IIA cervical cancer,” The Lancet, vol. 350, no. 9077, pp. 535–540, 1997. View at Publisher · View at Google Scholar · View at Scopus
  3. B. A. Goff, H. G. Muntz, P. J. Paley, H. K. Tamimi, W.-J. Koh, and B. E. Greer, “Impact of surgical staging in women with locally advanced cervical cancer,” Gynecologic Oncology, vol. 74, no. 3, pp. 436–442, 1999. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. J. A. Cosin, J. M. Fowler, M. D. Chen, P. J. Paley, L. F. Carson, and L. B. Twiggs, “Pretreatment surgical staging of patients with cervical carcinoma: the case for lymph node debulking,” Cancer, vol. 82, no. 11, pp. 2241–2248, 1998. View at Publisher · View at Google Scholar · View at Scopus
  5. I. Vistad, S. D. Fosså, and A. A. Dahl, “A critical review of patient-rated quality of life studies of long-term survivors of cervical cancer,” Gynecologic Oncology, vol. 102, no. 3, pp. 563–572, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. I. Vistad, M. Cvancarova, S. D. Fosså, and G. B. Kristensen, “Postradiotherapy morbidity in long-term survivors after locally advanced cervical cancer: how well do physicians' assessments agree with those of their patients?” International Journal of Radiation Oncology Biology Physics, vol. 71, no. 5, pp. 1335–1342, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. M. Frumovitz, C. C. Sun, L. R. Schover et al., “Quality of life and sexual functioning in cervical cancer survivors,” Journal of Clinical Oncology, vol. 23, no. 30, pp. 7428–7436, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. W. A. Peters III, P. Y. Liu, R. J. Barrett II et al., “Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix,” Journal of Clinical Oncology, vol. 18, no. 8, pp. 1606–1613, 2000. View at Google Scholar · View at Scopus
  9. M. E. Potter, R. D. Alvarez, H. M. Shingleton, S.-J. Soong, and K. D. Hatch, “Early invasive cervical cancer with pelvic lymph node involvement: to complete or not to complete radical hysterectomy?” Gynecologic Oncology, vol. 37, no. 1, pp. 78–81, 1990. View at Publisher · View at Google Scholar · View at Scopus
  10. S. D. Richard, T. C. Krivak, A. Castleberry et al., “Survival for stage IB cervical cancer with positive lymph node involvement: a comparison of completed vs. abandoned radical hysterectomy,” Gynecologic Oncology, vol. 109, no. 1, pp. 43–48, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. K. V. Fox, C. A. Shah, E. M. Swisher et al., “An evaluation of cervical cancer in women age sixty and over,” Gynecologic Oncology, vol. 109, no. 1, pp. 53–58, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. T. Girinski, M. H. Pejovic-Lenfant, J. Bourhis et al., “Prognostic value of hemoglobin concentrations and blood transfusions in advanced carcinoma of the cervix treated by radiation therapy: results of a retrospective study of 386 patients,” International Journal of Radiation Oncology Biology Physics, vol. 16, no. 1, pp. 37–42, 1989. View at Google Scholar · View at Scopus
  13. D. S. Kapp, D. Fischer, and E. Gutierrez, “Pretreatment prognostic factors in carcinoma of the uterine cervix: a multivariable analysis of the effect of age, stage, histology and blood counts on survival,” International Journal of Radiation Oncology Biology Physics, vol. 9, no. 4, pp. 445–455, 1983. View at Google Scholar · View at Scopus
  14. J. J. Caro, M. Salas, A. Ward, and G. Goss, “Anemia as an independent prognostic factor for survival in patients with cancer: a systematic, quantitative review,” Cancer, vol. 91, no. 12, pp. 2214–2221, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. P. W. Grigsby, B. A. Siegel, and F. Dehdashti, “Lymph node staging by positron emission tomography in patients with carcinoma of the cervix,” Journal of Clinical Oncology, vol. 19, no. 17, pp. 3745–3749, 2001. View at Google Scholar · View at Scopus
  16. P. G. Rose, L. P. Adler, M. Rodriguez, P. F. Faulhaber, F. W. Abdul-Karim, and F. Miraldi, “Positron emission tomography for evaluating para-aortic nodal metastasis in locally advanced cervical cancer before surgical staging: a surgicopathologic study,” Journal of Clinical Oncology, vol. 17, no. 1, pp. 41–45, 1999. View at Google Scholar · View at Scopus
  17. A. Loft, A. K. Berthelsen, H. Roed et al., “The diagnostic value of PET/CT scanning in patients with cervical cancer: a prospective study,” Gynecologic Oncology, vol. 106, no. 1, pp. 29–34, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  18. J. D. Wright, F. Dehdashti, T. J. Herzog et al., “Preoperative lymph node staging of early-stage cervical carcinoma by [F18]-fluoro-2-deoxy-D-glucose-positron emission tomography,” Cancer, vol. 104, no. 11, pp. 2484–2491, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  19. N. F. Hacker, G. V. Wain, and J. L. Nicklin, “Resection of bulky positive lymph nodes in patients with cervical carcinoma,” International Journal of Gynecological Cancer, vol. 5, no. 4, pp. 250–256, 1995. View at Publisher · View at Google Scholar · View at Scopus
  20. M. P. Hopkins and G. W. Morley, “Radical hysterectomy versus radiation therapy for stage IB squamous cell cancer of the cervix,” Cancer, vol. 68, no. 2, pp. 272–277, 1991. View at Publisher · View at Google Scholar · View at Scopus
  21. G. L. Bremer, H. W. H. M. Van Der Putten, G. A. J. Dunselman, and J. De Haan, “Early stage cervical cancer: aborted versus completed radical hysterectomy,” European Journal of Obstetrics Gynecology and Reproductive Biology, vol. 47, no. 2, pp. 147–151, 1992. View at Google Scholar
  22. C. W. Whitney and F. B. Stehman, “The abandoned radical hysterectomy: a Gynecologic Oncology Group study,” Gynecologic Oncology, vol. 79, no. 3, pp. 350–356, 2000. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  23. C. A. Leath III, J. M. Straughn Jr., J. M. Estes et al., “The impact of aborted radical hysterectomy in patients with cervical carcinoma,” Gynecologic Oncology, vol. 95, no. 1, pp. 204–207, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  24. P. Suprasert, J. Srisomboon, K. Charoenkwan et al., “Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation,” International Journal of Gynecological Cancer, vol. 15, no. 3, pp. 498–502, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus