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Obstetrics and Gynecology International
Volume 2010 (2010), Article ID 834275, 4 pages
http://dx.doi.org/10.1155/2010/834275
Case Report

Contrast-Enhanced Dynamic MR Imaging of Uterine Fibroids as a Potential Predictor of Patient Eligibility for MR Guided Focused Ultrasound (MRgFUS) Treatment for Symptomatic Uterine Fibroids

1Department of Diagnostic Radiology, CHA Bundang Medical Center, CHA University, 351, Yatap-dong, Bundang-gu, Sungnam-si, Gyunggi-do 463-712, Republic of Korea
2Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, CHA University, Gyunggi-do 463-712, Republic of Korea

Received 23 January 2010; Accepted 8 July 2010

Academic Editor: Liselotte Mettler

Copyright © 2010 Sang-Wook Yoon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a non-invasive treatment approach for symptomatic uterine fibroids. One imaging characteristic considered in selecting patients who may benefit from MRgFUS of their uterine fibroids is the signal intensity of the fibroid compared with surrounding myometrium on T2-weighted MR images. Previous reports suggest that hyper-intense fibroids are less amenable to MRgFUS compared with iso- or hypo-intense fibroids. In this case study, we utilized contrast-enhanced dynamic MR imaging to further characterize the vascularity of a hyper-intense fibroid. Based on the results of dynamic T1-weighted contrast-enhanced images, we assumed that the hyper-intense appearance resulted from high fluid content rather than high vascularity and predicted that the fibroid would respond to MRgFUS. The patient underwent the MRgFUS without complication and reported significant decrease in fibroid symptoms at 3 and 12 months post-treatment. This case suggests that pre-treatment dynamic contrast-enhanced imaging used in conjunction with T2-weighted imaging may improve the criteria for selecting uterine fibroids amenable to treatment with MRgFUS, potentially leading to improved patient outcomes.