Genetics of Endometrial Cancers

Table 1

Clinical and pathological features of endometrial carcinoma.

	Type I (EEC)	Type II (NEEC)
Age	Pre- and perimenopausal	Postmenopausal
Behavior	Stable	Progressive
Grade	Low	High
Hyperplasia-precursor	Present	Absent
Unopposed estrogen	Present	Absent
Myometrial invasion	Minimal	Deep
Specific Subtypes	Endometrioid carcinoma	Non-endometrioid carcinoma
Prevalence	70–80%	10–20%
Risk factors	Obesity, anovulation, nulliparity and exogenous estrogen exposure	In atropic endometrium