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Obstetrics and Gynecology International
Volume 2011, Article ID 896896, 8 pages
Research Article

Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKB /AKT and Induces Apoptosis

1The Reproductive Molecular Biology Laboratory, Division of Maternal-Fetal Medicine, Departments of Obstetrics and Gynecology and Biochemistry and Molecular Biology, The University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
2Clinic of Fetal Medicine and Maternal Medicine and Obstetrics and Gynecology, 263 Farmington Avenue Farmington, CT 06030, USA
3Department of Biochemistry and Microbiology, Faculty of Pharmacy, University of Kalamoon, P.O. Box: 222, Deirattiah, Syria
4Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, MSC 105580, 2211 Lomas Boulevard. NE, Albuquerque, NM 87131, USA
5The Center of Reproductive Medicine and Infertility at the Weill Cornell University, CRMI 1305 York Avenue, New York, NY 10021, USA
6Department of Obstetrics and Gynecology, The University of Iowa, Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA

Received 31 March 2011; Accepted 3 June 2011

Academic Editor: Edmund F. Funai

Copyright © 2011 J. Bolnick et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

J. Bolnick, L. Albitar, L. L. Laidler, R. Abdullah, and K. K. Leslie, “Blocking Epidermal Growth Factor Receptor Signalin… /AKT and Induces Apoptosis,” Obstetrics and Gynecology International, vol. 2011, Article ID 896896, 8 pages, 2011.