Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKB/AKT and Induces Apoptosis
Figure 4
Apoptosis in response to Iressa and serum starvation. HTR-8/SVneo cells as visualized by an Olympus laser confocal microscope at 1000 x. (a) HTR-8/SVneo cells grown in complete media, (b) HTR-8/SVneo cells grown in serum-starved media for 24 h, and (c) HTR-8/SVneo cells were grown in serum-starved media with Iressa (1 μM). Graph (d) represents the average percent of apoptotic cells in complete media (a), serum-starved media (b), Iressa + complete media (picture not shown), and Iressa in serum-depleted media (c). Error bars = standard error of the mean.
