Research Article

Protein Kinase Cα Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells

Figure 1

PKCα activates an estrogen responsive promoter. Ishikawa cells were transiently transfected with 0.5 μg pEREluc, 0.3 μg pCMVβ, and the indicated amounts of pmyrPKCα or vector control (pCDNA3). Luciferase activity was normalized to β-galactosidase and promoter activity expressed as fold increase over control. Data are mean ± s.d. .
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