Review Article

Contemporary Clinical Management of Endometrial Cancer

Table 11

Selected treatment controversies in endometrial cancer.

Question/controversyComment

Role of lymphadenectomy in low risk ASTEC trial did not support but results not universally accepted
Prognostic value of peritoneal cytologyRemoved as a staging variable recently but still to be collected and reported
Role of radiation in intermediate riskLocal control improved but no overall survival benefit
Best adjuvant for high-risk diseaseRecent data supports carboplatin/paclitaxel combination
Should targeted therapies be utilizedFurther clinical and basic science research required; mTOR inhibtors promising