Autologous Cord Blood Therapy for Infantile Cerebral Palsy: From Bench to Bedside

Table 1

Therapeutic responses to autologous cord blood infusion according to clinical characteristics and infused TNC counts. This paper is available online at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369209/ [45].

UPN

Sex

Age (Mo)

BW (Kg)

TNC (10^7/kg)

Dx

Tx response

Type

GA

Possible causes

DDST II

PEDI

GMFCS

MACS

Overall

1

M

80

13

5.38

Quad

Full

Unknown

N

Y

N

N

N

2

F

24

10

6.72

Quad

Full

HIE, PVL

N

N

Y

N

N

3

F

91

14

10.92

Quad

Full

Unknown

N

Y

N

N

N

4

F

91

19.5

2.87

Quad

Full

HIE, MAS

N

N

N

N

N

5

F

82

18.1

4.36

Di

Full

Unknown

N

Y

N

N

N

6

F

28

7.2

9.58

Quad

Full

Unknown

N

N

N

N

N

7

M

31

11.2

5.72

Quad

Full

Strep meningitis

N

N

N

N

N

8

F

71

21.4

2.89

Hemi

Full

Polymicrogyria

Y

Y

N

N

Y

9

M

43

16.4

0.6

Hemi

Preterm

HIE, PVL

Y

Y

N

Y

Y

10

F

75

9.4

10.63

Quad

Full

HIE, MAS

N

N

N

N

N

11

F

53

15.3

5.88

Hemi

Full

Unknown

N

Y

N

N

Y

12

F

40

12.7

2.44

Hemi

Preterm

HIE, PVL

N

Y

N

Y

Y

13

M

29

10.8

6.85

Di

Preterm

HIE, PVL

Y

Y

N

N

Y

14

M

67

15

5.26

Quad

Full

Unknown

N

N

N

N

N

15

M

78

20

5.14

Hemi

Full

HIE, ICH, Infarction

Y

Y

N

N

N

16

F

71

17.9

2.86

Di

Full

Unknown

N

Y

N

N

N

17

F

58

11.6

15.65

Quad

Preterm

HIE, PVL

N

Y

N

N

N

18

M

29

11.3

0.71

Quad

Full

Unknown

N

Y

N

N

N

19

F

30

11.5

3.29

Hemi

Full

MCA infarction

N

N

N

N

N

20

M

23

10.9

2.25

Quad

Full

Unknown

N

Y

N

N

N

UPN: unique patient number, BW: body weight, TNC: total nucleated cells, Dx: diagnosis, Tx: treatment, GA: gestational age, DDST  II: Denver developmental screening test II, PEDI: pediatric evaluation of disability inventory, GMFCS: Gross Motor Function Classification System, MACS: Manual Ability Classification System, Quad: quadriplegic, Di: diplegic, Hemi: hemiplegic, Full: full term, HIE: hypoxic ischemic encephalopathy, PVL: periventricular leukomalacia, MAS: meconium aspiration pneumonia, Strep: streptococcal, ICH: intracranial hemorrhage, MCA: middle cerebral artery, N: no, and Y: yes.