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Obstetrics and Gynecology International
Volume 2015, Article ID 817849, 13 pages
Review Article

N-Acetylcysteine for Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

1Department of Pharmacology, SAL Institute of Pharmacy, Ahmadabad, Gujarat 380060, India
2Department of Pharmaceutical Systems and Policy, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA
3Department of Biopharmaceutical Sciences, Bernard J. Dunn School of Pharmacy, Shenandoah University, Winchester, VA 22601, USA
4Department of Endocrinology, Post-Graduate Medical Education and Research Institute (PGIMER), Chandigarh 160012, India

Received 13 May 2014; Accepted 31 August 2014

Academic Editor: Curt W. Burger

Copyright © 2015 Divyesh Thakker et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [8 citations]

The following is the list of published articles that have cited the current article.

  • Ahmed M. Maged, Heba Elsawah, Aly Abdelhafez, Ahmed Bakry, and Walaa AI Mostafa, “ The adjuvant effect of metformin and N -acetylcysteine to clomiphene citrate in induction of ovulation in patients with Polycystic Ovary Syndrome ,” Gynecological Endocrinology, vol. 31, no. 8, pp. 635–638, 2015. View at Publisher · View at Google Scholar
  • Olga Papalou, Victor M. Victor, and Evanthia Diamanti-Kandarakis, “Oxidative Stress in Polycystic Ovary Syndrome,” Current Pharmaceutical Design, vol. 22, no. 18, pp. 2709–2722, 2016. View at Publisher · View at Google Scholar
  • Luigi Barrea, Paolo Marzullo, Giovanna Muscogiuri, Carolina Di Somma, Massimo Scacchi, Francesco Orio, Gianluca Aimaretti, Annamaria Colao, and Silvia Savastano, “Source and amount of carbohydrate in the diet and inflammation in women with polycystic ovary syndrome,” Nutrition Research Reviews, pp. 1–11, 2018. View at Publisher · View at Google Scholar
  • Chau T. Tay, Anju E. Joham, Danielle S. Hiam, Moustafa A. Gadalla, Jyotsna Pundir, Shakila Thangaratinam, Helena J. Teede, and Lisa J. Moran, “Pharmacological and surgical treatment of nonreproductive outcomes in polycystic ovary syndrome: An overview of systematic reviews,” Clinical Endocrinology, 2018. View at Publisher · View at Google Scholar
  • Yuehui Zhang, Wei Zhao, Hongfei Xu, Min Hu, Xiaozhu Guo, Wenyan Jia, Guoqi Liu, Juan Li, Peng Cui, Susanne Lager, Amanda Nancy Sferruzzi‐Perri, Wei Li, Xiao‐ke Wu, Yanhua Han, Mats Brännström, Linus R Shao, and Håkan Billig, “Hyperandrogenism and insulin resistance‐induced fetal loss: evidence for placental mitochondrial abnormalities and elevated reactive oxygen species production in pregnant rats that mimic the clinical features of polycystic ovary syndrome,” The Journal of Physiology, 2019. View at Publisher · View at Google Scholar
  • Ibrahim A. El Sharkwy, and Walled M. Abd El Aziz, “ Randomized controlled trial of N ‐acetylcysteine versus l ‐carnitine among women with clomiphene‐citrate‐resistant polycystic ovary syndrome ,” International Journal of Gynecology & Obstetrics, 2019. View at Publisher · View at Google Scholar
  • Y. Li, X. Ruan, J. Liebenthron, M. Montag, Q. Zhou, W. Kong, J. Du, F. Jin, S. Li, J. Cheng, H. Wang, and A. O. Mueck, “Ovarian tissue cryopreservation for patients with premature ovary insufficiency caused by cancer treatment: optimal protocol,” Climacteric, vol. 22, no. 4, pp. 383–389, 2019. View at Publisher · View at Google Scholar
  • Jyotsna Pundir, David Charles, Luca Sabatini, Danielle Hiam, Sonia Jitpiriyaroj, Helena Teede, Arri Coomarasamy, Lisa Moran, and Shakila Thangaratinam, “Overview of systematic reviews of non-pharmacological interventions in women with polycystic ovary syndrome,” Human Reproduction Update, 2019. View at Publisher · View at Google Scholar