Research Article
The Prognostic Value of Baseline Lymphocyte, Neutrophil, and Monocyte Counts in Locally Advanced Cervical Carcinoma Treated with Radiation
Table 4
Multivariate analysis of potential factors associated with OS and PFS.
| Variable | Overall survival | Progression-free survival | Hazard ratio [95% CI] | | Hazard ratio [95% CI] | |
| Age (years) | 1.00 [0.98–1.02] | | 1.00 [0.99–1.02] | 0.659 | Race | | | | | White | Reference | | Reference | | Black | 1.30 [0.27–6.26] | 0.742 | 1.26 [0.37–4.29] | 0.714 | Other | 1.36 [0.27–6.61] | 0.707 | 1.19 [0.35–4.07] | 0.785 | BMI (kg/m2) | 1.00 [0.97–1.02] | 0.899 | 1.00 [0.98–1.03] | 0.925 | Smoker | | | | | Smoker | Reference | | Reference | | Nonsmoker | 1.37 [0.79–2.37] | 0.267 | 1.08 [0.68–1.72] | 0.737 | Histology | | | | | Squamous | Reference | | Reference | | Adenocarcinoma | 0.06 [0.01–0.64] | 0.020 | 0.23 [0.03–1.90] | 0.167 | Adenosquamous | 0.10 [0.01–1.14] | 0.063 | 0.44 [0.05–4.07] | 0.471 | Stage | | | | | IB2 | Reference | | Reference | | IIA | 0.37 [0.12–1.21] | 0.099 | 0.42 [0.18–1.00] | 0.050 | IIB | 0.28 [0.07–1.14] | 0.075 | 0.33 [0.12–0.85] | 0.022 | IIIA | 0.69 [0.25–1.88] | 0.463 | 0.40 [0.18–0.89] | 0.025 | IIIB | 1.61 [0.47–5.55] | 0.449 | 0.48 [0.14–1.62] | 0.235 | IVA | 1.28 [0.52–3.12] | 0.590 | 0.92 [0.46–1.84] | 0.822 | Treatment | | | | | RT alone | Reference | | Reference | | CRT | 1.65 [0.63–4.31] | 0.305 | 1.64 [0.74–3.60] | 0.221 | Circulating Neutrophil count | 1.08 [0.99–1.17] | 0.102 | 1.12 [1.03–1.21] | 0.006 | Circulating Lymphocyte count | 0.67 [0.47–0.96] | 0.027 | 0.79 [0.60–1.06] | 0.113 | Circulating Monocyte count | 1.08 [0.99–1.17] | 0.201 | 1.07 [0.49–2.35] | 0.858 |
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