Table 3: White matter damage (WMD) and obstetrical variables. Data as mean (SD) and 95% confidence intervals in morphometric index z-score bands of 4,725 term-born neonates at 37–43 weeks gestation as compared with the reference (25 to <75%).

Morphometric index (centile)NMeanSD95% confidence interval
Lower limitUpper limit

White matter damage present<10%4720.030.170.010.010.001
10 to <25%7090.010.080.000.00n.s.
25 to <75%2,3620.010.100.000.01Reference
75 to <90%7100.010.070.000.00n.s.
90 to <100%4720.030.160.010.010.011
Total4,7250.010.110.000.01
EPH gestosis<10%4720.140.560.090.19<0.001
10 to <25%7090.070.250.050.09n.s.
25 to <75%2,3620.050.220.040.06Reference
75 to <90%7100.060.230.040.07n.s.
90 to <100%4720.110.310.080.130.001
Total4,7250.070.290.060.08
Twins/multiples<10%4720.150.350.110.18<0.001
10 to <25%7090.050.210.030.06<0.001
25 to <75%2,3620.010.100.010.01Reference
75 to <90%7100.000.000.000.00n.s.
90 to <100%4720.000.050.000.01n.s.
Total4,7250.030.160.020.03
Growth retardation (IUGR)<10%4720.250.430.210.28<0.001
10 to <25%7090.020.140.010.03n.s.
25 to <75%2,3620.000.050.000.00Reference
75 to <90%7100.000.040.000.00n.s.
90 to <100%4720.000.000.000.00n.s.
Total4,7250.030.170.020.03
Cardiotocography, pathologic (CTG)<10%4720.230.420.190.26<0.001
10 to <25%7090.120.320.090.14n.s.
25 to <75%2,3620.090.280.070.10Reference
75 to <90%7100.090.290.070.11n.s.
90 to <100%4720.080.280.060.11n.s.
Total4,7250.110.310.100.11
Stained amniotic fluid<10%4720.040.210.030.06n.s.
10 to <25%7080.040.180.020.05n.s.
25 to <75%2,3620.040.200.040.05Reference
75 to <90%7100.090.280.070.11<0.001
90 to <100%4720.070.250.040.09n.s.
Total4,7240.050.220.040.06
Prolonged or obstructed labor<10%4720.080.270.050.10n.s.
10 to <25%7090.090.280.070.11n.s.
25 to <75%2,3620.110.310.100.12Reference
75 to <90%7100.170.380.150.20<0.001
90 to <100%4720.210.410.170.24<0.001
Total4,7250.120.330.110.13
Mode of delivery<10%4721.470.831.391.540.001
10 to <25%7091.380.861.311.44n.s.
25 to <75%2,3621.300.721.271.33Reference
75 to <90%7101.400.791.341.450.033
90 to <100%4721.420.741.361.490.013
Total4,7251.350.771.331.38
Presentation<10%4711.230.641.181.29<0.001
10 to <25%7081.140.511.101.18n.s.
25 to <75%2,3601.100.431.081.11Reference
75 to <90%7101.070.381.051.10n.s.
90 to <100%4721.070.381.041.11n.s.
Total4,7211.110.461.101.12
Gender<10%4721.600.491.551.640.013
10 to <25%7081.570.501.531.61n.s.
25 to <75%2,3581.520.501.501.54Reference
75 to <90%7091.420.491.391.46<0.001
90 to <100%4721.260.451.221.30<0.001
Total4,7191.490.501.481.51