Assessment of Diagnostic Values among CA-125, RMI, HE4, and ROMA for Cancer Prediction in Women with Nonfunctional Ovarian Cysts

Table 3

Compare the sensitivity, specificity, PPV, and NPV of CA-125, HE4, and HE4 at new cutoff point and ROMA.

	CA-125 (>35 IU/mL)	HE4 (>150 pMol/L)	HE4 (>70 pMol/L)	ROMA
Sensitivity (%)	87.9	53.4	74.1	79.3
Specificity (%)	46.2	97.8	86.5	79.8
PPV (%)	29.8	86.1	59.2	50.5
NPV (%)	93.6	89	93.3	93.7
AUC	0.81	0.77	0.87	0.89