Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage

Table 20

Analysis of the combined effects of TLR9 and IL-6 SNPs on the risk of miscarriage with multiple logistic regression.

	Estimate	Std. error	z value	Pr (>|z|)
(Intercept)	1.0609	0.3867	2.743	0.00609
TLR9 GG + IL-6 GG	−1.6587	0.5390	−3.078	0.00209
TLR9 AA + IL-6 GG	0.3254	0.8801	0.370	0.71156
TLR9 GA + IL-6 GG	0.3254	0.8801	0.370	0.71156
TLR9 GG + IL-6 CC	−18.6269	1251.0541	−0.015	0.98812
TLR9 AA + IL-6 CC	16.5052	1615.1039	0.010	0.99185
TLR9 GA + IL-6 CC	−1.0609	0.8060	−1.316	0.18808
TLR9 GG + IL-6 GC	−1.3745	0.4906	−2.802	0.00508
TLR9 AA + IL-6 GC	2.1172	1.0914	1.940	0.05240

Significance codes: 0 ‘’ 0.001 ‘’ 0.01 ‘’ 0.05 ‘.’ 0.1 ‘ ’ 1.