Evaluating the Agreement of Risk Categorization for Fetal Down Syndrome Screening between Ultrasound-Based Gestational Age and Menstrual-Based Gestational Age by Maternal Serum Markers
Table 5
Agreement of risk categorization between US-based and LMP-based screening.
US-based screening
LMP-based screening
Total
Kappa index
High risk
Low risk
First trimester
High risk
255 (6.3%)
85 (2.1%)
340 (8.4%)
0.592
Low risk
213 (5.3%)
3502 (86.4%)
3715 (91.6%)
Total
468 (11.5%)
3587 (88.5%)
4055 (100.0%)
Second trimester
High risk
485 (12.1%)
102 (2.5%)
587 (14.6%)
0.622
Low risk
340 (8.5%)
3089 (76.9%)
3249 (85.4%)
Total
825 (20.5%)
3191 (79.5%)
4016 (100.0%)
First and second trimester
High risk
740 (9.2%)
187 (2.3%)
927 (11.5%)
0.615
Low risk
553 (6.9%)
6591 (81.7%)
7144 (88.5%)
Total
1293 (16.0%)
6778 (84.0%)
8071 (100.0%)
Bold indicates the number (%) of agreement of the two types of screening.
