Obstetrics and Gynecology International

Pathogenesis of Endometriosis and Uterine Fibroids


Publishing date
24 May 2013
Status
Published
Submission deadline
04 Jan 2013

1Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy

2MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK

3Department of Obstetrics and Gynecology, University of Minas Gerais, Belo Horizonte, MG, Brazil


Pathogenesis of Endometriosis and Uterine Fibroids

Description

Endometriosis and uterine fibroids are important pathological conditions of the uterus.Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity and represents one of the most gynecological disorders affecting 10-15% of all women of reproductive age and >30% of all infertile women. Uterine fibroids (leiomyomas or myomas) are benign tumors of the myometrium. Uterine leiomyomas affect as many as 77% of women in reproductive age, although 20-50% of women are symptomatic.

Although they are nonneoplastic conditions, they heavily impact upon women's health and fertility and are a common indication for surgery and the socioeconomic cost is huge. The mechanisms of formation remain unclear.The knowledge and the understanding of the pathogenesis of these conditions are essential to develop successful medical therapies and to understand the mechanisms of action of the currently available therapies and are of interest to basic researcher, clinical researcher, and clinicians. This journal will be an excellent resource for researchers and physicians and will provide state-of-the-art information on these very common benign uterine/pelvic conditions with such a major impact on women's quality of life.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to further the understanding of the pathogenesis of endometriosis, uterine fibroids, and adenomyosis. We are particularly interested in articles describing morphological, histological, biochemical, genetic, and epigenetic aspects pertaining to those conditions, as well as the pathogenetic mechanisms and new avenues of enquiry (novel hypotheses). Potential topics include, but are not limited to:

  • Genetic factors
  • Epigenetic factors
  • Oxidative stress
  • Inflammation
  • Stem cell
  • Deregulation of proliferation
  • Fibrotic process
  • Steroid hormones
  • Growth factors
  • Cytokines and chemokines
  • Association with cancer

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ogi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ogi/pendo/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 656571
  • - Editorial

Pathogenesis of Endometriosis and Uterine Fibroids

Pasquapina Ciarmela | Hilary Critchley | ... | Fernando M. Reis
  • Special Issue
  • - Volume 2013
  • - Article ID 528376
  • - Research Article

The Natural History of Uterine Leiomyomas: Light and Electron Microscopic Studies of Fibroid Phases, Interstitial Ischemia, Inanosis, and Reclamation

Gordon P. Flake | Alicia B. Moore | ... | Darlene Dixon
  • Special Issue
  • - Volume 2013
  • - Article ID 285103
  • - Research Article

The Natural History of Uterine Leiomyomas: Morphometric Concordance with Concepts of Interstitial Ischemia and Inanosis

Gordon P. Flake | Alicia B. Moore | ... | Darlene Dixon
  • Special Issue
  • - Volume 2013
  • - Article ID 173184
  • - Review Article

Uterine Fibroids: Pathogenesis and Interactions with Endometrium and Endomyometrial Junction

Andrea Ciavattini | Jacopo Di Giuseppe | ... | Pasquapina Ciarmela
  • Special Issue
  • - Volume 2013
  • - Article ID 527041
  • - Review Article

Interplay between Misplaced Müllerian-Derived Stem Cells and Peritoneal Immune Dysregulation in the Pathogenesis of Endometriosis

Antonio Simone Laganà | Emanuele Sturlese | ... | Onofrio Triolo
  • Special Issue
  • - Volume 2013
  • - Article ID 859619
  • - Review Article

Angiogenesis and Endometriosis

Ana Luiza L. Rocha | Fernando M. Reis | Robert N. Taylor
  • Special Issue
  • - Volume 2013
  • - Article ID 879618
  • - Clinical Study

Gene Expression of Leptin and Long Leptin Receptor Isoform in Endometriosis: A Case-Control Study

Andrea Prestes Nácul | Sheila Bunecker Lecke | ... | Poli Mara Spritzer
Obstetrics and Gynecology International
 Journal metrics
Acceptance rate8%
Submission to final decision102 days
Acceptance to publication25 days
CiteScore2.100
Impact Factor-
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