Obstetrics and Gynecology International

Controversies in the Management of Endometrial Cancer


Publishing date
01 Apr 2010
Status
Published
Submission deadline
01 Oct 2009

1Department of Obstetrics, Gynecology and Reproductive Sciences, Temple University, USA

2Queensland Centre for Gynaecological Cancer, University of Queensland, Australia

3Division of Medical Oncology, University of British Columbia, Canada

4Department of Obstetrics and Gynecology, Mayo Clinic Arizona, USA

5Department of Gynecology, Lahey Clinic, USA


Controversies in the Management of Endometrial Cancer

Description

Endometrial carcinoma is the most common gynecologic malignancy in developed countries. Its most common symptom, postmenopausal bleeding, causes women to seek medical evaluation early, which leads to early diagnosis. The FIGO staging of this cancer is surgical-pathological. Most patients have stage I disease at diagnosis. The majority are cured by simple hysterectomy and bilateral salpingo-oophorectomy.

International, and even regional and local, differences of opinion exist as to the need to perform lymph node dissection and the extent of the lymphadenectomy in these patients. There is the need to improve the understanding of the risk-to-benefit ratio when extended surgery is performed on the typical population of women with endometrial carcinoma whose average age is 62 years and have comorbidities.

There is also debate about the need for, appropriate type of, cost-effectiveness, and efficacy of adjuvant therapy. Many patients are not surgical candidates due to comorbidities. There is a need to better understand the expected outcomes with nonsurgical therapy.

For this special issue we are calling for manuscripts that address these issues. We seek manuscripts (original research, reviews, evidence-based clinical opinion) which provide the best evidence to guide clinical practice.

The topics to be addressed include:

  • Prevention, diagnosis, and pretherapy evaluation
  • Molecular profile of endometrial carcinoma
  • Nonsurgical therapy of endometrial carcinoma
  • Type of hysterectomy (transabdominal, transvaginal, LAVH)
  • Assessing the need for and extent of lymph node dissection
  • Adjuvant therapies for endometrial carcinoma (to include molecular targeted therapy)

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ogi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/, according to the following timetable:


Articles

  • Special Issue
  • - Volume 2010
  • - Article ID 894587
  • - Editorial

Controversies in the Management of Endometrial Cancer

Enrique Hernandez | Andreas Obermair | ... | Robert Mclellan
  • Special Issue
  • - Volume 2010
  • - Article ID 486164
  • - Review Article

The LH/hCG Axis in Endometrial Cancer: A New Target in the Treatment of Recurrent or Metastatic Disease

A. Arcangeli | I. Noci | ... | G. F. Scarselli
  • Special Issue
  • - Volume 2010
  • - Article ID 181963
  • - Review Article

Controversies in Surgical Staging of Endometrial Cancer

R. Seracchioli | S. Solfrini | ... | S. Venturoli
  • Special Issue
  • - Volume 2010
  • - Article ID 862908
  • - Review Article

Controversies in the Management of Endometrial Carcinoma

Ying Zhang | Jian Wang
  • Special Issue
  • - Volume 2010
  • - Article ID 638165
  • - Review Article

Controversies in the Management of Endometrial Cancer

V. Masciullo | G. Amadio | ... | G. Scambia
  • Special Issue
  • - Volume 2010
  • - Article ID 984013
  • - Review Article

Genetics of Endometrial Cancers

Tsuyoshi Okuda | Akihiko Sekizawa | ... | Takashi Okai
  • Special Issue
  • - Volume 2010
  • - Article ID 162363
  • - Review Article

Molecular Profiling of Endometrial Malignancies

Norasate Samarnthai | Kevin Hall | I-Tien Yeh
  • Special Issue
  • - Volume 2010
  • - Article ID 580971
  • - Review Article

Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management

Laura M. S. Seeber | Ronald P. Zweemer | ... | Paul J. van Diest
  • Special Issue
  • - Volume 2010
  • - Article ID 850812
  • - Review Article

Diagnostic Strategies for Postmenopausal Bleeding

M. C. Breijer | A. Timmermans | ... | B. C. Opmeer
  • Special Issue
  • - Volume 2010
  • - Article ID 490219
  • - Clinical Study

Systemic Lymphadenectomy Cannot Be Recommended for Low-Risk Corpus Cancer

Takao Hidaka | Akitoshi Nakashima | ... | Shigeru Saito
Obstetrics and Gynecology International
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