Research Article

Internalization of Staphylococcus aureus in Lymphocytes Induces Oxidative Stress and DNA Fragmentation: Possible Ameliorative Role of Nanoconjugated Vancomycin

Figure 14

Quantitative estimation of DNA fragmentation assay by diphenylamine (DPA) assay in control, 100 mg/kg bw/day vancomycin, 500 mg/kg bw/day vancomycin, 100 mg/kg bw/day nanoconjugated vancomycin, 500 mg/kg bw/day nanoconjugated vancomycin, VSSA infection control, VSSA infection + 100 mg/kg bw/day vancomycin, VSSA infection + 100 mg/kg bw/day nanoconjugated vancomycin, VRSA infection control, VRSA infection + 500 mg/kg bw/day vancomycin, VRSA infection + 500 mg/kg bw/day nanoconjugated vancomycin for 10-day treated lymphocyte. Values are expressed as mean ± SEM, . *indicates significant difference ( ) compared to control group. #indicates significant difference ( ) compared to infection control group.
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