Research Article

Royal Jelly Modulates Oxidative Stress and Apoptosis in Liver and Kidneys of Rats Treated with Cisplatin

Table 2

The effects of royal jelly administration on MDA, GSH, GSH-PX, GST, and SOD levels in liver and kidneys of rats treated with CDDP.

GroupsParameters
MDAGSHGSH-PxGSTSOD
(nmol/g protein)(μmol/g protein)(U/g protein)(μmol/g protein)(U/g protein)
LiverKidneyLiverKidneyLiverKidneyLiverKidneyLiverKidney

C38.50 ± 9.50a13.50± 1.40a130.75 ± 9.50a40.75± 0.25a95.50 ± 8.40a95.50 ± 6.50a75.50± 6.50a45.50 ± 12.50a680.50 ± 47.30a630.50 ± 22.70a
RJ37.50 ± 6.90a16.45± 0.75a133.30 ± 7.50a41.30± 0.30a109.50 ± 6.50a90.50 ± 10.30a92.80 ± 6.30a42.50 ± 10.75a755.50 ± 43.80a620.75 ± 35.50a
CD DP60.50 ± 6.50b32.50 ± 2.40b92.50 ± 8.50b21.50 ± 0.20b70.50 ± 7.30b42.75 ± 8.20b53.70 ± 7.50b18.50 ± 9.50b510.20 ± 45.50b480.30 ± 43.30b
RJ + CDDP49.50 ± 6.50c21.30 ± 0.90c115.80 ± 7.90c37.50 ± 0.20c90.80 ± 6.50c72.50 ± 9.50c63.50 ± 7.70c30.50 ± 13.50c595.50 ± 28.50c520.30 ± 24.50c

Different superscripts a, b, c in the same column indicate significant differences between groups ( ).   , means ± S.E.M. C: Control, RJ: royal jelly, CDDP: cisplatin.