Intensification of Doxorubicin-Related Oxidative Stress in the Heart by Hypothyroidism Is Not Related to the Expression of Cytochrome P450 NADPH-Reductase and Inducible Nitric Oxide Synthase, As Well As Activity of Xanthine Oxidase

<table>Representative Western Blot analysis for P450R protein in cardiac muscle homogenates. Beta-actin is shown as a loading control. Densitometric analysis (mean ± SD) of total P450R content, expressed as percent changes with respect to the control group, which has been set at 100%. *<i>P</i> &lt; 0.05 versus control and proper DOX group.</table>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Intensification of Doxorubicin-Related Oxidative Stress in the Heart by Hypothyroidism Is Not Related to the Expression of Cytochrome P450 NADPH-Reductase and Inducible Nitric Oxide Synthase, As Well As Activity of Xanthine Oxidase 

Figure 2 | Intensification of Doxorubicin-Related Oxidative Stress in the Heart by Hypothyroidism Is Not Related to the Expression of Cytochrome P450 NADPH-Reductase and Inducible Nitric Oxide Synthase, As Well As Activity of Xanthine Oxidase 