Antioxidant Capacity of Flavonoids in Hepatic Microsomes Is not Reflected by Antioxidant Effects In Vivo

Table 3

Weights and plasma concentrations of flavonoids and α-tocopherol in vitamin E deficient rats repleted for 2 weeks with 100 mg/kg of either α-tocopherol, quercetin, kaempferol or myricetin.

Parameter	Dietary inclusion
	−Vitamin E	+dα-tocopherol	+Quercetin	+Kaempferol	+Myricetin
Weight (g)	398 ± 11	394 ± 14	393 ± 11	398 ± 9	397 ± 7
dα-tocopherol (nmol/L)	1.16 ± 0.12	12.91±0.12^∗	0.91 ± 0.12	1.00 ± 0.07	1.04 ± 0.09
Quercetin (μmol/L)	Trace	Trace	1.48 ± 0.18	Trace	Trace
Kaempferol (μmol/L)	Trace	Trace	Trace	0.47 ± 0.06	Trace
Myricetin (μmol/L)	nd	nd	nd	nd	nd

Results are mean ± SEM of 6 rats/group. ^*Significantly different from −Vitamin E group (𝑃<0.001). Trace indicates that peak heights were too small to quantify; nd: no detectable compound.