Bisphenol A Induces Hepatotoxicity through Oxidative Stress in Rat Model

Table 6

The effect of BPA on the gene expression level of antioxidant enzymes, GSHPx, CAT, GR, and GST, in rat liver tissues.

Treatment groups	GSHPx	CAT	GR	GST
Control	9.3 ± 1.43	8.34 ± 1.5	10.3 ± 1.2	12.3 ± 1.4
BPA 0.1 mg/kg	8.7 ± 0.9	7.82 ± 0.91	9.26 ± 1.2	11.97 ± 0.6
BPA 1 mg/kg	8.45 ± 0.3	7.25 ± 0.3	8.65 ± 0.6	11.4 ± 0.4
BPA 10 mg/kg	6.63 ± 0.02	6.5 ± 0.2^*	6.54 ± 0.3^*	8.8 ± 0.5
BPA 50 mg/kg	0.52 ± 0.01^*	0.54 ± 0.01^*	0.57 ± 0.01^*	0.7 ± 0.05^*

The effect of BPA on the gene expression of antioxidant enzymes, glutathione peroxidase (GSHPx), catalase (CAT), glutathione transferase (GST), and glutathione reductase (GR) in liver tissues. Data were presented as the mean of fold expression ± SEM.
^*indicates significant change from control 𝑃<0.05 using ANOVA followed by Tukey-Kramer as a post-ANOVA test.