Research Article

Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats

Table 1

Glomerular hemodynamic findings 30 days after 5/6 nephrectomy.

Control5/6NX5/6NX + CURCUR

KW (g)
Hct (%)
SNFF (%)
FFP (mm Hg)
Pc (mm Hg)
Kf (nL·sec·mm Hg)
CA (g/100 mL)
πA (mm Hg)
CE (g/100 mL)
πE (mm Hg)

CUR: curcumin, 5/6 NX: five-sixths nephrectomy, KW: kidney weigth, Hct: Hematocrit, SNFF: single-nephron filtration fraction, FFP: Free flow pressure, : Peritubular capillary pressure, : ultrafiltration coefficient, : afferent protein concentration, : afferent oncotic pressure, : efferent protein concentration, : efferent oncotic pressure. Data are mean ± SEM, . Two way ANOVA followed by Bonferroni. ** versus 5/6NX.